Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase In Vitro and Lipolysis In Vivo
DC Field | Value | Language |
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dc.contributor.author | Kim, Young Sook | - |
dc.contributor.author | Lee, Youngseop | - |
dc.contributor.author | Kim, Junghyun | - |
dc.contributor.author | Sohn, Eunjin | - |
dc.contributor.author | Kim, Chan Sik | - |
dc.contributor.author | Lee, Yun Mi | - |
dc.contributor.author | Jo, Kyuhyung | - |
dc.contributor.author | Shin, Sodam | - |
dc.contributor.author | Song, Yoojin | - |
dc.contributor.author | Kim, Joo Hwan | - |
dc.contributor.author | Kim, Jin Sook | - |
dc.date.available | 2020-02-29T09:48:09Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2012-12 | - |
dc.identifier.issn | 1741-427X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17586 | - |
dc.description.abstract | To identify effective herb to treat obesity, we screened 115 herbal extracts for inhibition of porcine pancreatic lipase (triacylg-ycerol acylhydrolase, EC 3.1.1.3) activity in vitro. Of the extracts tested, Cudrania tricuspidata leaves exhibited the most pronounced inhibitory effect on lipase activity with an IC5(0) value of 9.91 mu g/mL. Antilipid absorption effects of C. tricuspidata leaves were examined in rats after oral administration of lipid emulsions containing 50 or 250 mg C. tricuspidata/kg body weight. Plasma triacylglycerol levels 2 h after the oral administration of emulsions containing C. tricuspidata were significantly reduced compared to the untreated group (P < 0.05). These results suggest that C. tricuspidata leaves may be useful for the treatment of obesity. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | HINDAWI PUBLISHING CORPORATION | - |
dc.relation.isPartOf | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | - |
dc.title | Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase In Vitro and Lipolysis In Vivo | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000312798000001 | - |
dc.identifier.doi | 10.1155/2012/878365 | - |
dc.identifier.bibliographicCitation | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, v.2012 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84872136221 | - |
dc.citation.title | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | - |
dc.citation.volume | 2012 | - |
dc.contributor.affiliatedAuthor | Kim, Joo Hwan | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | MEDICINAL-PLANT EXTRACTS | - |
dc.subject.keywordPlus | ACTINIDIA-ARGUTA | - |
dc.subject.keywordPlus | ANTI-LIPASE | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | ROOTS | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | MICE | - |
dc.relation.journalResearchArea | Integrative & Complementary Medicine | - |
dc.relation.journalWebOfScienceCategory | Integrative & Complementary Medicine | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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