Polypyrrole/Graphene Quantum Dot Composites as a Sensor Media for Epinephrine
- Authors
- Le, Thi Hoa; Lee, Dal Ho; Kim, Ji Hyeon; Park, Sang Joon
- Issue Date
- Jul-2020
- Publisher
- AMER SCIENTIFIC PUBLISHERS
- Keywords
- Graphene Quantum Dots; Polypyrrole; Epinephrine; Fluorescence Quenching
- Citation
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.20, no.7, pp.4005 - 4010
- Journal Title
- JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- Volume
- 20
- Number
- 7
- Start Page
- 4005
- End Page
- 4010
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17592
- DOI
- 10.1166/jnn.2020.17588
- ISSN
- 1533-4880
- Abstract
- In this paper, we discuss a new biosensor for simple and rapid detection of epinephrine (EP) based on polypyrrole/graphene quantum dot (PPy/GQD) composites. Presence of amine groups on the PPy backbone leads to surface passivation of GQDs. As a result, the composites exhibit strong fluorescence emission, which can be up to three times that of pristine GQDs. In neutral to alkaline solution, the EP on the surface of PPy/GQD composites is converted to a quinone, which triggers the fluorescence quenching of PPy/GQD composites via a photoinduced electron transfer process. Hence, the concentration of EP can be effectively monitored by measuring the variation in the fluorescence signal of PPy/GQD composites. The quenched fluorescence intensity of PPy/GQDs was proportional to the concentration of EP (0.7-400 mu M). We used our method to determine the concentration of EP in human serum samples and obtained satisfactory results.
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Collections - IT융합대학 > 전자공학과 > 1. Journal Articles
- 공과대학 > 화공생명공학과 > 1. Journal Articles
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