VITAMIN D DEFICIENCY AND NEUROLOGIC OUTCOME AFTER SUDDEN CARDIAC ARREST
DC Field | Value | Language |
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dc.contributor.author | Cha, Jung-Joon | - |
dc.contributor.author | Wi, Jin | - |
dc.date.available | 2020-03-03T07:43:19Z | - |
dc.date.created | 2020-02-24 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1073-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17945 | - |
dc.description.abstract | Background: Vitamin D deficiency is related to various cardiovascular diseases, including sudden cardiac arrest (SCA). This study investigated the association of vitamin D level with neurologic outcome and mortality after resuscitation from SCA. Patients and Methods: We enrolled patients who were successfully resuscitated from out-of-hospital cardiac arrest of presumed cardiac cause in Severance Cardiovascular Hospital as a prospective cohort registry. Baseline blood samples including pH, lactate, and vitamin D were obtained without fluid replacement just after hospital admission. Outcome was assessed by cerebral performance category (CPC) score at 1 month after SCA. Favorable outcome was defined as survival with CPC score of 1 or 2, whereas unfavorable one as death or survival with CPC scores of 3 through 5. Severe vitamin D deficiency was defined as 25(OH)D <10 ng/mL. Results: A total of 163 patients were included. Overall 96 (59%) patients had a favorable neurologic outcome, whereas 67 patients (41%) showed unfavorable outcome, including 37 (23%) mortality. Patients with unfavorable outcome were likely to be female and have initial non-shockable rhythm, longer arrest time, severe shock, diabetes, and baseline renal dysfunction. In multivariate analysis, severe vitamin D deficiency was one of the poor prognostic factors of both unfavorable neurologic outcome and mortality after SCA. Conclusions: Vitamin D deficiency is very prevalent and strongly associated with both unfavorable neurologic outcome and mortality in patients resuscitated from SCA. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | SHOCK | - |
dc.title | VITAMIN D DEFICIENCY AND NEUROLOGIC OUTCOME AFTER SUDDEN CARDIAC ARREST | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000509683400002 | - |
dc.identifier.doi | 10.1097/SHK.0000000000001335 | - |
dc.identifier.bibliographicCitation | SHOCK, v.52, no.6, pp.E146 - E152 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85074965652 | - |
dc.citation.endPage | E152 | - |
dc.citation.startPage | E146 | - |
dc.citation.title | SHOCK | - |
dc.citation.volume | 52 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Wi, Jin | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Cerebral performance category | - |
dc.subject.keywordAuthor | resuscitation | - |
dc.subject.keywordAuthor | sudden cardiac arrest | - |
dc.subject.keywordAuthor | vitamin D deficiency | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PROGNOSIS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordPlus | CARE | - |
dc.subject.keywordPlus | MEN | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalResearchArea | Hematology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Critical Care Medicine | - |
dc.relation.journalWebOfScienceCategory | Hematology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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