Effects of Preoperative Malnutrition on Postoperative Surgical Outcomes and Quality of Life of Elderly Patients with Periampullary Neoplasms: A Single-Center Prospective Cohort Study
DC Field | Value | Language |
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dc.contributor.author | Kim, Eunjung | - |
dc.contributor.author | Lee, Doo-Ho | - |
dc.contributor.author | Jang, Jin-Young | - |
dc.date.available | 2020-03-03T07:44:27Z | - |
dc.date.created | 2020-02-24 | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 1976-2283 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17987 | - |
dc.description.abstract | Background/Aims: We investigated the effect of preoperative malnutrition on postoperative surgical outcomes in elderly patients undergoing pancreatoduodenectomy for periampullary neoplasms. Methods: This prospective cohort study enrolled 154 patients aged >= 65 years with periampullary neoplasms. Using the Mini Nutritional Assessment tool, patients were categorized into three groups according to their preoperative nutritional status: well-nourished (13.0%), at-risk-of-malnutrition (59.7%), and malnourished (27.3%). Results: Significant intergroup differences were observed in preoperative body mass index (25.6 +/- 2.4 kg/m(2) [well-nourished] vs 23.4 +/- 2.6 kg/m(2) [at-risk-of-malnutrition] vs 21.1 +/- 2.8 kg/m(2) [malnourished], p<0.001). The overall morbidity significantly differed between the well-nourished and malnourished groups (20% vs 50.0%, p=0.024). The rates of clinically significant postoperative pancreatic fistula were significantly different among groups (p=0.035). Univariate and multivariate analyses showed that the at-risk-of-malnutrition or malnourished status (hazard ratio [HR], 3.45; p=0.037) and intraoperative blood loss (HR, 1.01; p=0.040) significantly affected the overall postoperative morbidity in elderly patients. Conclusions: Before surgery, 87.0% of patients were classified into the at-risk-of-malnutrition or malnourished group. Compared with well-nourished patients, patients with nutritional issues showed a higher overall surgical morbidity. Improved preoperative nutritional status leads to favorable surgical outcomes in elderly patients. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | EDITORIAL OFFICE GUT & LIVER | - |
dc.relation.isPartOf | GUT AND LIVER | - |
dc.title | Effects of Preoperative Malnutrition on Postoperative Surgical Outcomes and Quality of Life of Elderly Patients with Periampullary Neoplasms: A Single-Center Prospective Cohort Study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000496945500013 | - |
dc.identifier.doi | 10.5009/gnl18469 | - |
dc.identifier.bibliographicCitation | GUT AND LIVER, v.13, no.6, pp.690 - 697 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85074964940 | - |
dc.citation.endPage | 697 | - |
dc.citation.startPage | 690 | - |
dc.citation.title | GUT AND LIVER | - |
dc.citation.volume | 13 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Lee, Doo-Ho | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Pancreatoduodenectomy | - |
dc.subject.keywordAuthor | Nutritional status | - |
dc.subject.keywordAuthor | Elderly | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | QUESTIONNAIRE | - |
dc.subject.keywordPlus | QLQ-C30 | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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