Recent Advances in the Discovery of Novel Antiprotozoal Agents
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Seong-Min | - |
dc.contributor.author | Kim, Min-Sun | - |
dc.contributor.author | Hayat, Faisal | - |
dc.contributor.author | Shin, Dongyun | - |
dc.date.available | 2020-03-03T07:44:41Z | - |
dc.date.created | 2020-02-24 | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/17996 | - |
dc.description.abstract | Parasitic diseases have serious health, social, and economic impacts, especially in the tropical regions of the world. Diseases caused by protozoan parasites are responsible for considerable mortality and morbidity, affecting more than 500 million people worldwide. Globally, the burden of protozoan diseases is increasing and is been exacerbated because of a lack of effective medication due to the drug resistance and toxicity of current antiprotozoal agents. These limitations have prompted many researchers to search for new drugs against protozoan parasites. In this review, we have compiled the latest information (2012-2017) on the structures and pharmacological activities of newly developed organic compounds against five major protozoan diseases, giardiasis, leishmaniasis, malaria, trichomoniasis, and trypanosomiasis, with the aim of showing recent advances in the discovery of new antiprotozoal drugs. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | MOLECULES | - |
dc.subject | VARIANT SURFACE GLYCOPROTEIN | - |
dc.subject | AMODIAQUINE-INDUCED AGRANULOCYTOSIS | - |
dc.subject | ASPARAGINE-LINKED OLIGOSACCHARIDES | - |
dc.subject | TRICHOMONAS-VAGINALIS INFECTION | - |
dc.subject | NEGLECTED PARASITIC INFECTIONS | - |
dc.subject | HUMAN AFRICAN TRYPANOSOMIASIS | - |
dc.subject | IN-VITRO ACTIVITY | - |
dc.subject | BIOLOGICAL EVALUATION | - |
dc.subject | DRUG DISCOVERY | - |
dc.subject | ANTILEISHMANIAL ACTIVITY | - |
dc.title | Recent Advances in the Discovery of Novel Antiprotozoal Agents | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000498055500075 | - |
dc.identifier.doi | 10.3390/molecules24213886 | - |
dc.identifier.bibliographicCitation | MOLECULES, v.24, no.21 | - |
dc.identifier.scopusid | 2-s2.0-85074271504 | - |
dc.citation.title | MOLECULES | - |
dc.citation.volume | 24 | - |
dc.citation.number | 21 | - |
dc.contributor.affiliatedAuthor | Lee, Seong-Min | - |
dc.contributor.affiliatedAuthor | Kim, Min-Sun | - |
dc.contributor.affiliatedAuthor | Hayat, Faisal | - |
dc.contributor.affiliatedAuthor | Shin, Dongyun | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | protozoan diseases | - |
dc.subject.keywordAuthor | parasitic | - |
dc.subject.keywordAuthor | giardiasis | - |
dc.subject.keywordAuthor | leishmaniasis | - |
dc.subject.keywordAuthor | malaria | - |
dc.subject.keywordAuthor | trichomoniasis | - |
dc.subject.keywordAuthor | trypanosomiasis | - |
dc.subject.keywordPlus | VARIANT SURFACE GLYCOPROTEIN | - |
dc.subject.keywordPlus | AMODIAQUINE-INDUCED AGRANULOCYTOSIS | - |
dc.subject.keywordPlus | ASPARAGINE-LINKED OLIGOSACCHARIDES | - |
dc.subject.keywordPlus | TRICHOMONAS-VAGINALIS INFECTION | - |
dc.subject.keywordPlus | NEGLECTED PARASITIC INFECTIONS | - |
dc.subject.keywordPlus | HUMAN AFRICAN TRYPANOSOMIASIS | - |
dc.subject.keywordPlus | IN-VITRO ACTIVITY | - |
dc.subject.keywordPlus | BIOLOGICAL EVALUATION | - |
dc.subject.keywordPlus | DRUG DISCOVERY | - |
dc.subject.keywordPlus | ANTILEISHMANIAL ACTIVITY | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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