Data on the stability of Prx1-associated snRNAs and mRNAs
- Authors
- Kim, Eun-Kyung; Ahn, Sung-Min; Jang, Ho Hee
- Issue Date
- Aug-2019
- Publisher
- ELSEVIER
- Keywords
- Peroxiredoxin1; Small nuclear RNA; RNA stability; Protein-RNA interaction
- Citation
- DATA IN BRIEF, v.25
- Journal Title
- DATA IN BRIEF
- Volume
- 25
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/18340
- DOI
- 10.1016/j.dib.2019.104309
- ISSN
- 2352-3409
- Abstract
- This data set is related to the research article entitled "Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression" (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis. (C) 2019 The Authors. Published by Elsevier Inc.
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