LI-RADS Classification and Prognosis of Primary Liver Cancers at Gadoxetic Acid-enhanced MRI
DC Field | Value | Language |
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dc.contributor.author | Choi, Sang Hyun | - |
dc.contributor.author | Lee, Seung Soo | - |
dc.contributor.author | Park, So Hyun | - |
dc.contributor.author | Kim, Kang Mo | - |
dc.contributor.author | Yu, Eunsil | - |
dc.contributor.author | Park, Yangsoon | - |
dc.contributor.author | Shin, Yong Moon | - |
dc.contributor.author | Lee, Moon-Gyu | - |
dc.date.available | 2020-02-27T04:41:55Z | - |
dc.date.created | 2020-02-05 | - |
dc.date.issued | 2019-02 | - |
dc.identifier.issn | 0033-8419 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/1888 | - |
dc.description.abstract | Purpose: To (a) evaluate the postsurgical prognostic implication of the Liver Imaging Reporting and Data System (LI-RADS) categories of primary liver cancers and (b) determine the performance of LI-RADS version 2017 in differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (IHCC) and combined hepatocellular-cholangiocarcinoma (cHCC-CC) at gadoxetic acid-enhanced MRI. Materials and Methods: In this retrospective study, 194 patients with cirrhosis and surgically proven single primary liver cancer (53 with cHCC-CC, 44 with IHCC, and 97 with HCC) were evaluated with gadoxetic acid-enhanced MRI between 2009 and 2014. The mean patient age was 57 years (age range, 30-83 years). There were 155 men with a mean age of 56 years (range, 30-81 years) and 39 women with a mean age of 58 years (range, 38-83 years). Two independent readers assigned an LI-RADS category for each nodule. Overall survival (OS), recurrence-free survival (RFS), and their associated factors were evaluated by using the Kaplan-Meier method, log-rank test, and Cox proportional hazard model. Results: In the multivariable analysis, the LI-RADS category was an independent factor for OS (hazard ratio, 4.2; P<.001) and RFS (hazard ratio, 2.6; P =.01). The LR-M category showed more correlation with poorer OS and RFS than did the LR-4 or LR-5 category for all primary liver cancers (P<.001 for both), HCCs (P =.01 and P<.001, respectively), and cHCC-CCs (P =.01 and P =.03, respectively). The LR-5 category had a sensitivity of 69% (67 of 97) and a specificity of 87% (84 of 97) in the diagnosis of HCC; most false-positive diagnoses (85%, 11 of 13) were the result of misclassification of cHCC-CCs. Conclusion: The Liver Imaging Reporting and Data System (LI-RADS) category was associated with postsurgical prognosis of primary liver cancers, independent of pathologic diagnosis. The LI-RADS enabled the correct classification of most hepatocellular carcinomas (HCCs) and intrahepatic cholangiocarcinomas, whereas differentiation of combined hepatocellular-cholangiocarcinoma from HCC was unreliable. (c) RSNA, 2018 | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | RADIOLOGICAL SOC NORTH AMERICA | - |
dc.relation.isPartOf | RADIOLOGY | - |
dc.subject | COMBINED HEPATOCELLULAR-CHOLANGIOCARCINOMA | - |
dc.subject | DATA SYSTEM V2014 | - |
dc.subject | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject | IMAGING FEATURES | - |
dc.subject | CARCINOMA | - |
dc.subject | CT | - |
dc.subject | DIFFERENTIATION | - |
dc.subject | TRANSPLANTATION | - |
dc.subject | PATTERNS | - |
dc.title | LI-RADS Classification and Prognosis of Primary Liver Cancers at Gadoxetic Acid-enhanced MRI | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000456444200021 | - |
dc.identifier.doi | 10.1148/radiol.2018181290 | - |
dc.identifier.bibliographicCitation | RADIOLOGY, v.290, no.2, pp.388 - 397 | - |
dc.identifier.scopusid | 2-s2.0-85060396859 | - |
dc.citation.endPage | 397 | - |
dc.citation.startPage | 388 | - |
dc.citation.title | RADIOLOGY | - |
dc.citation.volume | 290 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Park, So Hyun | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | COMBINED HEPATOCELLULAR-CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | DATA SYSTEM V2014 | - |
dc.subject.keywordPlus | INTRAHEPATIC CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | IMAGING FEATURES | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | TRANSPLANTATION | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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