한국에서 신경근차단제와 길항제의 사용 실태Current use of neuromuscular blocking agents and antagonists in Korea: a 2018 survey
- Other Titles
- Current use of neuromuscular blocking agents and antagonists in Korea: a 2018 survey
- Authors
- 김진선; 한정우; 이재호; 최재문; 김하정; 성태윤; 김용범; 신용섭; 양홍석
- Issue Date
- Oct-2019
- Publisher
- 대한마취통증의학회
- Keywords
- Neostigmine; Neuromuscular blocking agents; Neuromuscular monitoring; Pyridostigmine bromide; Sugammadex.
- Citation
- Anesthesia and Pain Medicine, v.14, no.4, pp 441 - 448
- Pages
- 8
- Journal Title
- Anesthesia and Pain Medicine
- Volume
- 14
- Number
- 4
- Start Page
- 441
- End Page
- 448
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/2199
- DOI
- 10.17085/apm.2019.14.4.441
- ISSN
- 1975-5171
- Abstract
- Background: Neuromuscular blocking agents (NMBAs) and neuromuscular monitoring in anesthetic management are integral for endotracheal intubation, better visualization of the surgical field, and prevention of residual neuromuscular blockade and pulmonary complications. Sugammadex is a drug that reduces risk of residual neuromuscular blockade, with more rapid recovery compared to anticholinesterase. The purpose of this study was to investigate current usage status of NMBAs and antagonist with neuromuscular monitoring, among anesthesiologists in Korea.
Methods: Anesthesiologists working in Korea were invited to participate in an online survey via email January 2–February 28, 2018. The questionnaire consisted of 45 items, including preferred NMBAs, antagonists, neuromuscular monitoring, and complications related to the use sugammadex. A total of 174 responses were analyzed.
Results: Rocuronium was a commonly used NMBA for endotracheal intubation (98%) of hospitals, and maintenance of anesthesia (83.3%) in of hospitals. Sugammadex, pyridostigmine, and neostigmine were used in 89.1%, 87.9%, and 45.4% of hospitals. Neuromuscular monitoring was employed in 79.3% of hospitals; however only 39.7% of hospitals used neuromuscular monitoring before antagonist administration. Usual dosage range of sugammadex was 2.1–4 mg/kg in 35.1% of hospitals, within 2 mg/kg in 34.5% of hospitals, and 1 vial regardless of body weight in 22.4% of hospitals. Sugammadexrelated complications were encountered by 14.9% of respondents.
Conclusions: This survey indicates several minor problems associated with the use of antagonists and neuromuscular monitoring. However, most anesthesiologists appear to have appropriate information regarding the usage of NMBAs and sugammadex.
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