Chemical constituents of Impatiens balsamina stems and their biological activities
DC Field | Value | Language |
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dc.contributor.author | Kim, D.H. | - |
dc.contributor.author | Lee, T.H. | - |
dc.contributor.author | Subedi, L. | - |
dc.contributor.author | Kim, S.Y. | - |
dc.contributor.author | Lee, K.R. | - |
dc.date.available | 2020-02-27T07:41:08Z | - |
dc.date.created | 2020-02-11 | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 1226-3907 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/2681 | - |
dc.description.abstract | The purification of the MeOH extract from Impatiens basamina by repeated column chromatography led to the isolation of one new tetrahydronaphthalene (1), together with eleven known compounds (2-12). The structure of the new compound (1) was determined by spectral data analysis (1H and13C-NMR,1H-1H COSY, HSQC, HMBC, NOESY, and HR-ESI-MS). Isolated compounds (1-12) were evaluated for their inhibitory effects on NO production in LPS-activated murine microglial BV-2 cells and their effects on NGF secretion from C6 glioma cells. Compounds 3, 7, and 10 reduced NO levels in LPS-activated murine microglial cells with IC50 values of 26.89, 25.59, and 44.21 µM, respectively. Compounds 1, 5, and 9 upregulated NGF secretion to 153.09 ± 4.66, 156.88 ± 8.86, and 157.34 ± 3.30%, respectively. © 2019, Korean Society of Pharmacognosy. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Pharmacognosy | - |
dc.relation.isPartOf | Natural Product Sciences | - |
dc.title | Chemical constituents of Impatiens balsamina stems and their biological activities | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.doi | 10.20307/nps.2019.25.2.130 | - |
dc.identifier.bibliographicCitation | Natural Product Sciences, v.25, no.2, pp.130 - 135 | - |
dc.identifier.kciid | ART002475851 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85071382442 | - |
dc.citation.endPage | 135 | - |
dc.citation.startPage | 130 | - |
dc.citation.title | Natural Product Sciences | - |
dc.citation.volume | 25 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Subedi, L. | - |
dc.contributor.affiliatedAuthor | Kim, S.Y. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Balsaminaceae | - |
dc.subject.keywordAuthor | Impatiens balsamina | - |
dc.subject.keywordAuthor | Neuroprotective effect | - |
dc.subject.keywordAuthor | Tetrahydronaphthalene | - |
dc.subject.keywordPlus | 1 beta 2 alpha 4 beta triol 1,2,3,4 tetrahydronaphthalene | - |
dc.subject.keywordPlus | 1 beta 2 beta 4 beta triol 1,2,3,4 tetrahydronaphthalene | - |
dc.subject.keywordPlus | 29 nor 20 oxolupeol | - |
dc.subject.keywordPlus | 4 hydroxybenzoic acid | - |
dc.subject.keywordPlus | 7r,8s dihydrodehydrodiconiferyl alcohol 9 beta o d glucopyranoside | - |
dc.subject.keywordPlus | alpha spinasterol | - |
dc.subject.keywordPlus | beta amyrin | - |
dc.subject.keywordPlus | erythrodiol | - |
dc.subject.keywordPlus | Impatiens balsamina extract | - |
dc.subject.keywordPlus | kaempferol 3 o beta d glucopyranoside | - |
dc.subject.keywordPlus | lupenone | - |
dc.subject.keywordPlus | lupeol | - |
dc.subject.keywordPlus | nicotiflorin | - |
dc.subject.keywordPlus | nitric oxide | - |
dc.subject.keywordPlus | phytochemical | - |
dc.subject.keywordPlus | plant extract | - |
dc.subject.keywordPlus | plant medicinal product | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | animal cell | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | biological activity | - |
dc.subject.keywordPlus | C6 cell line (glioma) | - |
dc.subject.keywordPlus | carbon nuclear magnetic resonance | - |
dc.subject.keywordPlus | cell viability | - |
dc.subject.keywordPlus | chemical composition | - |
dc.subject.keywordPlus | chemical structure | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | cytotoxicity | - |
dc.subject.keywordPlus | drug synthesis | - |
dc.subject.keywordPlus | electrospray mass spectrometry | - |
dc.subject.keywordPlus | enzyme linked immunosorbent assay | - |
dc.subject.keywordPlus | heteronuclear multiple bond correlation | - |
dc.subject.keywordPlus | heteronuclear single quantum coherence | - |
dc.subject.keywordPlus | high performance liquid chromatography | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | human cell | - |
dc.subject.keywordPlus | IC50 | - |
dc.subject.keywordPlus | Impatiens | - |
dc.subject.keywordPlus | mass fragmentography | - |
dc.subject.keywordPlus | mouse | - |
dc.subject.keywordPlus | MTT assay | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | phytochemistry | - |
dc.subject.keywordPlus | plant stem | - |
dc.subject.keywordPlus | proton nuclear magnetic resonance | - |
dc.subject.keywordPlus | thin layer chromatography | - |
dc.subject.keywordPlus | upregulation | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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