Acid/base alterations during major abdominal surgery: 6% hydroxyethyl starch infusion versus 5% albumin
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwak, Hyun Jeong | - |
dc.contributor.author | Lim, Oh Kyung | - |
dc.contributor.author | Baik, Jae Myung | - |
dc.contributor.author | Jo, Youn Yi | - |
dc.date.available | 2020-02-27T08:41:19Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-12 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3002 | - |
dc.description.abstract | Background: To compare the effects of intraoperative infusions of balanced electrolyte solution (BES)-based hydroxyethyl starch (HES) and saline-based albumin on metabolic acidosis and acid/base changes during major abdominal surgery conducted using Stewart's approach. Methods: Forty patients, aged 20-65 years, undergoing major abdominal surgery, were randomly assigned to the HES group (n = 20; received 500 ml of BES-based 6% HES 130/0.4) or the albumin group (n = 20; received 500 ml of normal saline-based 5% albumin). Acid-base parameters were measured and calculated using results obtained from arterial blood samples taken after anesthesia induction (T1), 2 hours after surgery commencement (T2), immediately after surgery (T3), and 1 hour after arriving at a postanesthetic care unit (T4). Results: Arterial pH in the HES group was significantly higher than that in the albumin group at T3 (7.40 +/- 0.04 vs. 7.38 +/- 0.04, P = 0.043), and pH values exhibited significant intergroup difference over time (P = 0.002). Arterial pH was significantly lower at T3 and T4 in the HES group and at T2, T3, and T4 in the albumin group than at Tl. Apparent strong ion difference (SIDa) was significantly lower at T2, T3, and T4 than at T1 in both groups. Total plasma weak nonvolatile acid (A(TOT)) was significantly lower in the HES group than in the albumin group at T2, T3 and T4 and exhibited a significant intergroup difference over time (P < 0.001). Conclusions: BES-based 6% HES infusion was associated with lower arterial pH values at the end of surgery than saline-based 5% albumin infusion, but neither colloid caused clinically significant metabolic acidosis (defined as an arterial pH < 7.35). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC ANESTHESIOLOGISTS | - |
dc.relation.isPartOf | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.subject | ACID-BASE STATUS | - |
dc.subject | ANION GAP | - |
dc.subject | SALINE | - |
dc.subject | STRATEGY | - |
dc.title | Acid/base alterations during major abdominal surgery: 6% hydroxyethyl starch infusion versus 5% albumin | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000451885700006 | - |
dc.identifier.doi | 10.4097/kja.d.18.27195 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF ANESTHESIOLOGY, v.71, no.6, pp.459 - 466 | - |
dc.identifier.kciid | ART002408997 | - |
dc.identifier.scopusid | 2-s2.0-85059217895 | - |
dc.citation.endPage | 466 | - |
dc.citation.startPage | 459 | - |
dc.citation.title | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.citation.volume | 71 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Kwak, Hyun Jeong | - |
dc.contributor.affiliatedAuthor | Lim, Oh Kyung | - |
dc.contributor.affiliatedAuthor | Baik, Jae Myung | - |
dc.contributor.affiliatedAuthor | Jo, Youn Yi | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Acid base | - |
dc.subject.keywordAuthor | Albumin | - |
dc.subject.keywordAuthor | Hydroxyethyl starch | - |
dc.subject.keywordPlus | ACID-BASE STATUS | - |
dc.subject.keywordPlus | ANION GAP | - |
dc.subject.keywordPlus | SALINE | - |
dc.subject.keywordPlus | STRATEGY | - |
dc.relation.journalResearchArea | Anesthesiology | - |
dc.relation.journalWebOfScienceCategory | Anesthesiology | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.