Characteristics of contrast-enhanced ultrasound in distinguishing small (<= 3 cm) hepatocellular carcinoma from intrahepatic cholangiocarcinoma
DC Field | Value | Language |
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dc.contributor.author | Shin, Seung Kak | - |
dc.contributor.author | Choi, Duck Joo | - |
dc.contributor.author | Kim, Ju Hyun | - |
dc.contributor.author | Kim, Yun Soo | - |
dc.contributor.author | Kwon, Oh Sang | - |
dc.date.available | 2020-02-27T09:41:01Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-10 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3273 | - |
dc.description.abstract | Contrast-enhanced ultrasound (CEUS) is highly accurate in depicting the vascularity of liver nodules. The aim of this study was to verify the characteristics of CEUS in distinguishing small (<= 3 cm) hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICC). A total of 65 patients with a liver nodule (HCC, n=58; ICC, n=7) smaller than 3 cm who underwent liver CEUS and pathologic confirmation were retrospectively reviewed. CEUS findings were compared with histopathologic and clinical data. Arterial-phase hyperenhancement and portal-delayed-phase wash-out on CEUS were observed in 77.6% (45/58) of HCCs and 85.7% (6/7) of ICCs. Time of arterial-phase hyperenhancement (11 seconds [6-20] vs 16 seconds [14-19], P=.008), time of portal-delayed-phase wash-out (65 seconds (15-260) vs 35 secconds (27-54), P=.002), and time interval between arterial-phase hyperenhancement and portal-delayed-phase wash-out (50 seconds [5-249] vs 19 seconds [13-35], P<.001) on CEUS were significantly different between HCCs and ICCs showing arterial-phase hyperenhancement and portal-delayed-phase wash-out. The sensitivity, specificity, positive predictive value, and negative predictive value of time interval more than 25 seconds between arterialphase hyperenhancement and portal-delayed-phase wash-out on CEUS for the differentiation of HCCs and ICCs were 91.1%, 83.3%, 97.6%, and 55.6%, respectively. The time interval between arterial-phase hyperenhancement and portal-delayed-phase wash-out on CEUS was the most sensitive indicator in distinguishing small HCC from ICC showing arterial-phase hyperenhancement and portal-delayed-phase wash-out. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | MEDICINE | - |
dc.title | Characteristics of contrast-enhanced ultrasound in distinguishing small (<= 3 cm) hepatocellular carcinoma from intrahepatic cholangiocarcinoma | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000452234800081 | - |
dc.identifier.doi | 10.1097/MD.0000000000012781 | - |
dc.identifier.bibliographicCitation | MEDICINE, v.97, no.41 | - |
dc.identifier.scopusid | 2-s2.0-85054888032 | - |
dc.citation.title | MEDICINE | - |
dc.citation.volume | 97 | - |
dc.citation.number | 41 | - |
dc.contributor.affiliatedAuthor | Shin, Seung Kak | - |
dc.contributor.affiliatedAuthor | Choi, Duck Joo | - |
dc.contributor.affiliatedAuthor | Kim, Ju Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Yun Soo | - |
dc.contributor.affiliatedAuthor | Kwon, Oh Sang | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | contrast-enhanced ultrasound | - |
dc.subject.keywordAuthor | hepatocellular carcinoma | - |
dc.subject.keywordAuthor | intrahepatic cholangiocarcinoma | - |
dc.subject.keywordPlus | APPARENT DIFFUSION-COEFFICIENT | - |
dc.subject.keywordPlus | PERIPHERAL CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | HEPATIC-FIBROSIS | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | AGREEMENT | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | CIRRHOSIS | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | NODULES | - |
dc.subject.keywordPlus | SONOVUE | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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