Comparison of Clinical Outcomes Between Ticagrelor and Prasugrel in Patients With ST-Segment Elevation Myocardial Infarction - Results From the Korea Acute Myocardial Infarction Registry-National Institutes of Health -
DC Field | Value | Language |
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dc.contributor.author | Kim, Min Chul | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.contributor.author | Sim, Doo Sun | - |
dc.contributor.author | Hong, Young Joon | - |
dc.contributor.author | Kim, Ju Han | - |
dc.contributor.author | Ahn, Youngkeun | - |
dc.contributor.author | Ahn, Tae Hoon | - |
dc.contributor.author | Seung, Ki Bae | - |
dc.contributor.author | Choi, Dong-Ju | - |
dc.contributor.author | Kim, Hyo-Soo | - |
dc.contributor.author | Gwon, Hyeon Cheol | - |
dc.contributor.author | Seong, In Whan | - |
dc.contributor.author | Hwang, Kyoung-Kook | - |
dc.contributor.author | Chae, Shung Chull | - |
dc.contributor.author | Hur, Seung Ho | - |
dc.contributor.author | Cha, Kwang Soo | - |
dc.contributor.author | Oh, Seok Kyu | - |
dc.contributor.author | Chae, Jei Keon | - |
dc.date.available | 2020-02-27T10:41:27Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3631 | - |
dc.description.abstract | Background: There is little information regarding comparison of ticagrelor and prasugrel in patients with ST-segment elevation myocardial infarction (STEMI). We sought to compare clinical outcomes between ticagrelor and prasugrel in STEMI. Methods and Results: A total of 1,440 patients with STEMI who underwent successful primary percutaneous coronary intervention were analyzed; the data were obtained from the Korea Acute Myocardial Infarction Registry-National Institutes of Health. Of the patients, 963 received ticagrelor, and 477 received prasugrel. The primary study endpoint was 12-month major adverse cardiac events (MACE), including cardiac death, myocardial infarction (MI), and target vessel revascularization (TVR). MACE occurred in 91 patients (6.3%) over the 1-year follow-up, and there were no differences in the incidence of MACE (hazard ratio [HR] 1.20, 95% confidence interval [CI] 0.76-1.91, P=0.438) between the 2 groups. Analysis by propensity score matching (429 pairs) did not significantly affect the results. The incidence of in-hospital major bleeding events was still comparable between the 2 groups (2.4% vs. 2.5%, odds ratio 0.75, 95% CI 0.30-1.86, P=0.532), and there was no significant difference in the incidence of MACE (5.4% vs. 5.8%, HR 0.98, 95% CI 0.56-1.74, P=0.951) after matching. Conclusions: Ticagrelor and prasugrel showed similar efficacy and safety profiles for treating STEMI in this Korean multicenter registry. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | JAPANESE CIRCULATION SOC | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.subject | ACUTE CORONARY SYNDROMES | - |
dc.subject | SUCCESSFUL REVASCULARIZATION | - |
dc.subject | CLOPIDOGREL | - |
dc.subject | INTERVENTION | - |
dc.subject | METAANALYSIS | - |
dc.subject | DEFINITIONS | - |
dc.subject | INHIBITOR | - |
dc.subject | TRIALS | - |
dc.title | Comparison of Clinical Outcomes Between Ticagrelor and Prasugrel in Patients With ST-Segment Elevation Myocardial Infarction - Results From the Korea Acute Myocardial Infarction Registry-National Institutes of Health - | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000439629100021 | - |
dc.identifier.doi | 10.1253/circj.CJ-18-0112 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, v.82, no.7, pp.1866 - + | - |
dc.identifier.scopusid | 2-s2.0-85049053659 | - |
dc.citation.endPage | + | - |
dc.citation.startPage | 1866 | - |
dc.citation.title | CIRCULATION JOURNAL | - |
dc.citation.volume | 82 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | Ahn, Tae Hoon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Percutaneous coronary intervention | - |
dc.subject.keywordAuthor | Prasugrel | - |
dc.subject.keywordAuthor | ST elevation myocardial infarction | - |
dc.subject.keywordAuthor | Ticagrelor | - |
dc.subject.keywordPlus | ACUTE CORONARY SYNDROMES | - |
dc.subject.keywordPlus | SUCCESSFUL REVASCULARIZATION | - |
dc.subject.keywordPlus | CLOPIDOGREL | - |
dc.subject.keywordPlus | INTERVENTION | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | DEFINITIONS | - |
dc.subject.keywordPlus | INHIBITOR | - |
dc.subject.keywordPlus | TRIALS | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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