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Cited 20 time in webofscience Cited 21 time in scopus
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Mutual Destruction of Deep Lung Tumor Tissues by Nanodrug-Conjugated Stealth Mesenchymal Stem Cells

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dc.contributor.authorKim, Sang-Woo-
dc.contributor.authorLee, Yeon Kyung-
dc.contributor.authorHong, Jeong Hee-
dc.contributor.authorPark, Jun-Young-
dc.contributor.authorChoi, Young-Ae-
dc.contributor.authorLee, Dong Un-
dc.contributor.authorChoi, Jungil-
dc.contributor.authorSym, Sun Jin-
dc.contributor.authorKim, Sang-Hyun-
dc.contributor.authorKhang, Dongwoo-
dc.date.available2020-02-27T10:42:49Z-
dc.date.created2020-02-07-
dc.date.issued2018-05-
dc.identifier.issn2198-3844-
dc.identifier.urihttps://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3814-
dc.description.abstractLung cancer is a highly malignant tumor, and targeted delivery of anti-cancer drugs to deep lung tumor tissue remains a challenge in drug design. Here, it is demonstrated that bone marrow mesenchymal stem cells armed with nanodrugs are highly targeted and mutually destructive with malignant lung cancer cells and successfully eradicate lung tumors tissues. Using this approach, the current clinical dose of anti-cancer drugs for the treatment of malignant lung tumors can be decreased by more than 100-fold without triggering immunotoxicity.-
dc.language영어-
dc.language.isoen-
dc.publisherWILEY-
dc.relation.isPartOfADVANCED SCIENCE-
dc.subjectCANCER-THERAPY-
dc.subjectCHEMOKINE RECEPTORS-
dc.subjectCHEMOTHERAPY-
dc.subjectDELIVERY-
dc.subjectDRUG-
dc.subjectIMMUNOTHERAPY-
dc.subjectCALCIUM-
dc.subjectGENE-
dc.subjectNANOPARTICLES-
dc.subjectINFLAMMATION-
dc.titleMutual Destruction of Deep Lung Tumor Tissues by Nanodrug-Conjugated Stealth Mesenchymal Stem Cells-
dc.typeArticle-
dc.type.rimsART-
dc.description.journalClass1-
dc.identifier.wosid000435852800015-
dc.identifier.doi10.1002/advs.201700860-
dc.identifier.bibliographicCitationADVANCED SCIENCE, v.5, no.5-
dc.identifier.scopusid2-s2.0-85042397674-
dc.citation.titleADVANCED SCIENCE-
dc.citation.volume5-
dc.citation.number5-
dc.contributor.affiliatedAuthorKim, Sang-Woo-
dc.contributor.affiliatedAuthorLee, Yeon Kyung-
dc.contributor.affiliatedAuthorHong, Jeong Hee-
dc.contributor.affiliatedAuthorPark, Jun-Young-
dc.contributor.affiliatedAuthorLee, Dong Un-
dc.contributor.affiliatedAuthorSym, Sun Jin-
dc.contributor.affiliatedAuthorKhang, Dongwoo-
dc.type.docTypeArticle-
dc.subject.keywordAuthorhoming abilities-
dc.subject.keywordAuthorin vivo safety-
dc.subject.keywordAuthorlung tumors-
dc.subject.keywordAuthormesenchymal stem cells-
dc.subject.keywordAuthormutual destruction-
dc.subject.keywordAuthornanodrug membrane conjugation-
dc.subject.keywordPlusCANCER-THERAPY-
dc.subject.keywordPlusCHEMOKINE RECEPTORS-
dc.subject.keywordPlusCHEMOTHERAPY-
dc.subject.keywordPlusDELIVERY-
dc.subject.keywordPlusDRUG-
dc.subject.keywordPlusIMMUNOTHERAPY-
dc.subject.keywordPlusCALCIUM-
dc.subject.keywordPlusGENE-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusINFLAMMATION-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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