Detailed Information

Cited 457 time in webofscience Cited 540 time in scopus
Metadata Downloads

Precisely printable and biocompatible silk fibroin bioink for digital light processing 3D printing

Authors
Kim, Soon HeeYeon, Yeung KyuLee, Jung MinChao, Janet RenLee, Young JinSeo, Ye BeenSultan, Md. TipuLee, Ok JooLee, Ji SeungYoon, Sung-ilHong, In-SunKhang, GilsonLee, Sang JinYoo, James J.Park, Chan Hum
Issue Date
24-Apr-2018
Publisher
NATURE PUBLISHING GROUP
Citation
NATURE COMMUNICATIONS, v.9
Journal Title
NATURE COMMUNICATIONS
Volume
9
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/3854
DOI
10.1038/s41467-018-03759-y
ISSN
2041-1723
Abstract
Although three-dimensional (3D) bioprinting technology has gained much attention in the field of tissue engineering, there are still several significant engineering challenges to overcome, including lack of bioink with biocompatibility and printability. Here, we show a bioink created from silk fibroin (SF) for digital light processing (DLP) 3D bioprinting in tissue engineering applications. The SF-based bioink (Sil-MA) was produced by a methacrylation process using glycidyl methacrylate (GMA) during the fabrication of SF solution. The mechanical and rheological properties of Sil-MA hydrogel proved to be outstanding in experimental testing and can be modulated by varying the Sil-MA contents. This Sil-MA bioink allowed us to build highly complex organ structures, including the heart, vessel, brain, trachea and ear with excellent structural stability and reliable biocompatibility. Sil-MA bioink is well-suited for use in DLP printing process and could be applied to tissue and organ engineering depending on the specific biological requirements.
Files in This Item
There are no files associated with this item.
Appears in
Collections
의과대학 > 의예과 > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Hong, In Sun photo

Hong, In Sun
College of Medicine (Premedical Course)
Read more

Altmetrics

Total Views & Downloads

BROWSE