Enhanced Production of Fatty Acids via Redirection of Carbon Flux in Marine Microalga Tetraselmis sp
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Han, Mi-Ae | - |
dc.contributor.author | Hong, Seong-Joo | - |
dc.contributor.author | Kim, Z-Hun | - |
dc.contributor.author | Cho, Byung-Kwan | - |
dc.contributor.author | Lee, Hookeun | - |
dc.contributor.author | Choi, Hyung-Kyoon | - |
dc.contributor.author | Lee, Choul-Gyun | - |
dc.date.available | 2020-02-27T11:42:50Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4126 | - |
dc.description.abstract | Lipids in microalgae are energy-rich compounds and considered as an attractive feedstock for biodiesel production. To redirect carbon flux from competing pathways to the fatty acid synthesis pathway of Tetraselmis sp., we used three types of chemical inhibitors that can block the starch synthesis pathway or photorespiration, under nitrogen-sufficient and nitrogendeficient conditions. The starch synthesis pathway in chloroplasts and the cytosol can be inhibited by 3-(3,4-dichlorophenyl)-1,1-dimethylurea and 1,2-cyclohexane diamine tetraacetic acid (CDTA), respectively. Degradation of glycine into ammonia during photorespiration was blocked by aminooxyacetate (AOA) to maintain biomass concentration. Inhibition of starch synthesis pathways in the cytosol by CDTA increased fatty acid productivity by 27% under nitrogen deficiency, whereas the blocking of photorespiration in mitochondria by AOA was increased by 35% under nitrogen-sufficient conditions. The results of this study indicate that blocking starch or photorespiration pathways may redirect the carbon flux to fatty acid synthesis. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.subject | LIGHT UPTAKE RATES | - |
dc.subject | CHLAMYDOMONAS-REINHARDTII | - |
dc.subject | GLUCOSE PYROPHOSPHORYLASE | - |
dc.subject | BIOMASS COMPOSITION | - |
dc.subject | GLYCOLATE PATHWAY | - |
dc.subject | GREEN MICROALGAE | - |
dc.subject | NITROGEN | - |
dc.subject | ALGAE | - |
dc.subject | NANNOCHLOROPSIS | - |
dc.subject | AMINOOXYACETATE | - |
dc.title | Enhanced Production of Fatty Acids via Redirection of Carbon Flux in Marine Microalga Tetraselmis sp | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000426920600011 | - |
dc.identifier.doi | 10.4014/jmb.1702.02064 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.28, no.2, pp.267 - 274 | - |
dc.identifier.kciid | ART002318793 | - |
dc.identifier.scopusid | 2-s2.0-85043585632 | - |
dc.citation.endPage | 274 | - |
dc.citation.startPage | 267 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.volume | 28 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Lee, Hookeun | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Tetraselmis sp. | - |
dc.subject.keywordAuthor | fatty acids | - |
dc.subject.keywordAuthor | carbohydrates | - |
dc.subject.keywordAuthor | nitrogen starvation | - |
dc.subject.keywordAuthor | chemical inhibitors | - |
dc.subject.keywordPlus | LIGHT UPTAKE RATES | - |
dc.subject.keywordPlus | CHLAMYDOMONAS-REINHARDTII | - |
dc.subject.keywordPlus | GLUCOSE PYROPHOSPHORYLASE | - |
dc.subject.keywordPlus | BIOMASS COMPOSITION | - |
dc.subject.keywordPlus | GLYCOLATE PATHWAY | - |
dc.subject.keywordPlus | GREEN MICROALGAE | - |
dc.subject.keywordPlus | NITROGEN | - |
dc.subject.keywordPlus | ALGAE | - |
dc.subject.keywordPlus | NANNOCHLOROPSIS | - |
dc.subject.keywordPlus | AMINOOXYACETATE | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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