Liquid crystal as sensing platforms for determining the effect of graphene oxide-based materials on phospholipid membranes and monitoring antibacterial activity
DC Field | Value | Language |
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dc.contributor.author | Wei, Yibin | - |
dc.contributor.author | Jang, Chang-Hyun | - |
dc.date.available | 2020-02-27T12:41:31Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-01 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4181 | - |
dc.description.abstract | Understanding the mechanism of the cellular interaction of graphene oxide (GO)-based materials is vital for their biomedical and environmental applications. In this study, we developed a promising method for imaging the interaction between chitosan (CS)-reinforced GO and the phospholipid membrane based on a nematic liquid crystal (LC) sensing platform. Direct observation of the CS-GO-induced rupture of the pre-adsorbed phospholipid monolayer supported by an LC thin film was achieved using a polarizing optical microscope (POM). The disruption process was clearly monitored in real-time using this method. Moreover, because lipids at the Gram-negative bacterial cell membrane could be transferred onto the interfaces of micro-meter-sized sessile LC droplets, we found the LC droplets could be used to distinguish live Escherichia coli (E. coli) cells from dead cells. CS-GO efficiently reduced the cellular integrity of E. coli which was detectable by LC droplets; thus, the LC-based approach could be used for monitoring the antibacterial activities of GO-related materials. These experimental LC sensing platforms offer simple and direct observation methods for evaluating the effect of GO-based materials on the cell membrane and may be useful in corresponding antibacterial applications. (C) 2017 Elsevier B.V. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.relation.isPartOf | SENSORS AND ACTUATORS B-CHEMICAL | - |
dc.subject | CHITOSAN | - |
dc.subject | SURFACES | - |
dc.subject | BACTERIA | - |
dc.subject | POLYELECTROLYTE | - |
dc.subject | NANOCOMPOSITES | - |
dc.subject | FABRICATION | - |
dc.subject | INTERFACES | - |
dc.subject | NANOSHEETS | - |
dc.subject | PROSPECTS | - |
dc.subject | DROPLETS | - |
dc.title | Liquid crystal as sensing platforms for determining the effect of graphene oxide-based materials on phospholipid membranes and monitoring antibacterial activity | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000413308000011 | - |
dc.identifier.doi | 10.1016/j.snb.2017.07.057 | - |
dc.identifier.bibliographicCitation | SENSORS AND ACTUATORS B-CHEMICAL, v.254, pp.72 - 80 | - |
dc.identifier.scopusid | 2-s2.0-85024387516 | - |
dc.citation.endPage | 80 | - |
dc.citation.startPage | 72 | - |
dc.citation.title | SENSORS AND ACTUATORS B-CHEMICAL | - |
dc.citation.volume | 254 | - |
dc.contributor.affiliatedAuthor | Wei, Yibin | - |
dc.contributor.affiliatedAuthor | Jang, Chang-Hyun | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Liquid crystal | - |
dc.subject.keywordAuthor | 4-Cyano-4-pentylbiphenyl | - |
dc.subject.keywordAuthor | Graphene oxide | - |
dc.subject.keywordAuthor | Chitosan | - |
dc.subject.keywordAuthor | Phospholipids | - |
dc.subject.keywordAuthor | Antibacterial | - |
dc.subject.keywordPlus | CHITOSAN | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | BACTERIA | - |
dc.subject.keywordPlus | POLYELECTROLYTE | - |
dc.subject.keywordPlus | NANOCOMPOSITES | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | INTERFACES | - |
dc.subject.keywordPlus | NANOSHEETS | - |
dc.subject.keywordPlus | PROSPECTS | - |
dc.subject.keywordPlus | DROPLETS | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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