Oncologic outcomes of adjuvant chemotherapy alone after radical surgery for stage IB-IIA cervical cancer patients
DC Field | Value | Language |
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dc.contributor.author | Lee, Kwang-Beom | - |
dc.contributor.author | Kim, Young Saing | - |
dc.contributor.author | Lee, Jong-Min | - |
dc.date.available | 2020-02-27T12:42:13Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018-01 | - |
dc.identifier.issn | 2005-0380 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4237 | - |
dc.description.abstract | Objective: To evaluate the oncologic outcomes of adjuvant chemotherapy (CT) alone after radical surgery. Methods: We retrospectively reviewed the medical records of patients who underwent type C radical hysterectomy and pelvic lymphadenectomy with or without paraaortic lymphadenectomy for stage IB-IIA cervical cancer from March 2006 to December 2014 at 2 academic medical centers in Korea. Adjuvant CT alone for patients who met the Sedlis criteria or had lymph node (LN) involvement. Chemotherapeutic regimens consisted of either platinum alone or platinum-based combination. Results: A total of 101 consecutive patients were included in the analysis. The median age was 46.0 years (range, 23-73). Seventy-four patients (73.3%) were clinically staged as IB1; 23 and 4 patients as IB2 and IIA, respectively. The median number of retrieved pelvic and paraaortic LNs (PALNs) were 55.0 (range, 16-101) and 10.0 (range, 2-30), respectively. LN involvement was observed in 25 patients (24.8%). After the median follow-up of 65 months, 14 patients (13.9%) developed disease recurrence. In all patients, the estimated 3-year disease-free survival (DFS) rate and 5-year overall survival (OS) rate were 90.7% and 90.6%, respectively. In patients who met the Sedlis criteria, the 3-year DFS and 5-year OS rates were 94.6% and 90.6%, respectively. Patients with LN metastasis showed a 3-year DFS rate of 79.4% and a 5-year OS rate of 90.6%. Conclusion: Adjuvant CT alone could be reasonable option for patients with surgical-pathologic risk factors after radical surgery in stage IB-IIA cervical cancer. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC GYNECOLOGY ONCOLOGY & COLPOSCOPY | - |
dc.relation.isPartOf | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
dc.subject | PELVIC RADIATION-THERAPY | - |
dc.subject | QUALITY-OF-LIFE | - |
dc.subject | FOLLOW-UP | - |
dc.subject | INTERMEDIATE-RISK | - |
dc.subject | RANDOMIZED-TRIAL | - |
dc.subject | HYSTERECTOMY | - |
dc.subject | LYMPHADENECTOMY | - |
dc.subject | IRRADIATION | - |
dc.subject | CARCINOMA | - |
dc.subject | RECURRENT | - |
dc.title | Oncologic outcomes of adjuvant chemotherapy alone after radical surgery for stage IB-IIA cervical cancer patients | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000416677900005 | - |
dc.identifier.doi | 10.3802/jgo.2018.29.e5 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GYNECOLOGIC ONCOLOGY, v.29, no.1 | - |
dc.identifier.kciid | ART002303851 | - |
dc.identifier.scopusid | 2-s2.0-85036548592 | - |
dc.citation.title | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
dc.citation.volume | 29 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Lee, Kwang-Beom | - |
dc.contributor.affiliatedAuthor | Kim, Young Saing | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Adjuvant Chemotherapy | - |
dc.subject.keywordAuthor | Drug Therapy | - |
dc.subject.keywordAuthor | Uterine Cervical Neoplasms | - |
dc.subject.keywordPlus | PELVIC RADIATION-THERAPY | - |
dc.subject.keywordPlus | QUALITY-OF-LIFE | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | INTERMEDIATE-RISK | - |
dc.subject.keywordPlus | RANDOMIZED-TRIAL | - |
dc.subject.keywordPlus | HYSTERECTOMY | - |
dc.subject.keywordPlus | LYMPHADENECTOMY | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | RECURRENT | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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