Effect of pharmaceutical care interventions on glycemic control in patients with diabetes: A systematic review and meta-analysis
- Authors
- Jeong, Sohyun; Lee, Minhee; Ji, Eunhee
- Issue Date
- Sep-2018
- Publisher
- Dove Medical Press Ltd.
- Keywords
- Diabetes; High-income country; Low-and middle-income country; Multidisciplinary team care; Pharmacist care
- Citation
- Therapeutics and Clinical Risk Management, v.14, pp.1813 - 1829
- Journal Title
- Therapeutics and Clinical Risk Management
- Volume
- 14
- Start Page
- 1813
- End Page
- 1829
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4319
- DOI
- 10.2147/TCRM.S169748
- ISSN
- 1176-6336
- Abstract
- Purpose: Diabetes is a chronic lifelong condition, and adherence to medications and self-monitoring of blood glucose are challenging for diabetic patients. The dramatic increase in the prevalence of diabetes is largely due to the incidence of type 2 diabetes in low-and middle-income countries (LMIc) besides high-income countries (HIc). We aimed to evaluate whether pharmacist care (PC) service model in LMIc and HIc could improve clinical outcomes in diabetic patients by performing a meta-analysis. Methods: PubMed, Embase, and ProQuest Dissertations Unlimited Published Literature database were searched to find publications pertaining to pharmacist-led intervention in patients with diabetes. The inclusion criteria were as follows: 1) randomized controlled trials, 2) confirmed diabetic patients (type 1 or type 2), 3) pharmaceutical care intervention by clinical pharmacist or/and multidisciplinary team, and 4) reporting HbA1c at baseline and end of study or the mean change in these values. Results: A total of 37 articles were included in the meta-analysis. The overall result was significant and in favor of PC intervention on HbA1c change (standard difference in mean values [SDM]: 0.379, 95% CI: 0.208–0.550, P<0.001). The stratified meta-analysis showed that PC was significant in both HIc (n=20; SDM: 0.351, 95% CI: 0.207–0.495) and LMIc (n=15; SDM: 0.426, 95% CI: 0.071–0.780). More than 6 months is needed to obtain adequate effects on clinical diabetes parameters. Conclusion: Our study presented that an adequate duration of pharmacist-led pharmaceutical care was effective in improving HbA1c in patients with diabetes in both LMIc and HIc. © 2018 Jeong et al.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - 약학대학 > 약학과 > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/4319)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.