Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases
DC Field | Value | Language |
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dc.contributor.author | Ganesan, Palanivel | - |
dc.contributor.author | Ramalingam, Prakash | - |
dc.contributor.author | Karthivashan, Govindarajan | - |
dc.contributor.author | Ko, Young Tag | - |
dc.contributor.author | Choi, Dong-Kug | - |
dc.date.available | 2020-02-27T15:43:52Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1178-2013 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5299 | - |
dc.description.abstract | Solid lipid nanoparticle (SLN) delivery systems have a wide applicability in the delivery of phyto-bioactive compounds to treat various chronic diseases, including diabetes, cancer, obesity and neurodegenerative diseases. The multiple benefits of SLN delivery include improved stability, smaller particle size, leaching prevention and enhanced lymphatic uptake of the bioactive compounds through oral delivery. However, the burst release makes the SLN delivery systems inadequate for the oral delivery of various phyto-bioactive compounds that can treat such chronic diseases. Recently, the surface-modified SLN (SMSLN) was observed to overcome this limitation for oral delivery of phyto-bioactive compounds, and there is growing evidence of an enhanced uptake of curcumin delivered orally via SMSLNs in the brain. This review focuses on different SLN and SMSLN systems that are useful for oral delivery of phyto-bioactive compounds to treat various chronic diseases. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | DOVE MEDICAL PRESS LTD | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.subject | BLOOD-BRAIN-BARRIER | - |
dc.subject | PROOF-OF-CONCEPT | - |
dc.subject | DRUG-DELIVERY | - |
dc.subject | IN-VIVO | - |
dc.subject | PARKINSON DISEASE | - |
dc.subject | CELLULAR UPTAKE | - |
dc.subject | OXIDATIVE STRESS | - |
dc.subject | PHYSICOCHEMICAL CHARACTERIZATION | - |
dc.subject | NEURODEGENERATIVE DISEASES | - |
dc.subject | POLYMERIC NANOPARTICLES | - |
dc.title | Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000428037100004 | - |
dc.identifier.doi | 10.2147/IJN.S155593 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF NANOMEDICINE, v.13, pp.1569 - 1583 | - |
dc.identifier.scopusid | 2-s2.0-85044338935 | - |
dc.citation.endPage | 1583 | - |
dc.citation.startPage | 1569 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.citation.volume | 13 | - |
dc.contributor.affiliatedAuthor | Ramalingam, Prakash | - |
dc.contributor.affiliatedAuthor | Ko, Young Tag | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | solid lipid nanoparticles | - |
dc.subject.keywordAuthor | surface-modified solid lipid nanoparticles | - |
dc.subject.keywordAuthor | chronic diseases | - |
dc.subject.keywordAuthor | phyto-bioactive compounds | - |
dc.subject.keywordAuthor | chitosan | - |
dc.subject.keywordPlus | BLOOD-BRAIN-BARRIER | - |
dc.subject.keywordPlus | PROOF-OF-CONCEPT | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | PARKINSON DISEASE | - |
dc.subject.keywordPlus | CELLULAR UPTAKE | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | PHYSICOCHEMICAL CHARACTERIZATION | - |
dc.subject.keywordPlus | NEURODEGENERATIVE DISEASES | - |
dc.subject.keywordPlus | POLYMERIC NANOPARTICLES | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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