Rapid Whole-Brain Gray Matter Imaging Using Single-Slab Three-Dimensional Dual-Echo Fast Spin Echo: A Feasibility Study
DC Field | Value | Language |
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dc.contributor.author | Lee, Hyunyeol | - |
dc.contributor.author | Kim, Eung Yeop | - |
dc.contributor.author | Sohn, Chul-Ho | - |
dc.contributor.author | Park, Jaeseok | - |
dc.date.available | 2020-02-27T16:43:43Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-11 | - |
dc.identifier.issn | 0740-3194 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5549 | - |
dc.description.abstract | Purpose: To achieve rapid, high resolution whole-brain gray matter (GM) imaging by developing a novel, single-slab three-dimensional dual-echo fast-spin-echo pulse sequence and GM-selective reconstruction. Methods: Unlike conventional GM imaging that uses time-consuming double-inversion-recovery preparation, the proposed pulse sequence was designed to have two split portions along the echo train, in which the first half was dedicated to yield short inversion recovery (IR)-induced white matter suppression and variable-flip-angle-induced two-step GM signal evolution while the second half cerebrospinal fluid-only signals. Multi-step variable-flip-angle schedules and sampling reordering were optimized to yield high GM signals while balancing cerebrospinal fluid signals between ECHOes. GM-selective images were then reconstructed directly from the weighted subtraction between ECHOes by solving a sparse signal recovery problem. In vivo studies were performed to validate the effectiveness of the proposed method over conventional double-inversion-recovery. Results: The proposed method, while achieving one millimeter isotropic, whole-brain GM imaging within 5.5 min, showed superior performance than conventional double-inversion-recovery in producing GM-only images without apparent artifacts and noise. Conclusion: We successfully demonstrated the feasibility of the proposed method in achieving whole-brain GM imaging in a clinically acceptable imaging time. The proposed method is expected to be a promising alternative to conventional double-inversion-recovery in clinical applications. (C) 2017 International Society for Magnetic Resonance in Medicine. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | MAGNETIC RESONANCE IN MEDICINE | - |
dc.subject | MULTIPLE-SCLEROSIS | - |
dc.subject | PULSE SEQUENCE | - |
dc.subject | INVERSION | - |
dc.subject | LESIONS | - |
dc.subject | RECONSTRUCTION | - |
dc.subject | OPTIMIZATION | - |
dc.subject | SUPPRESSION | - |
dc.subject | IMAGES | - |
dc.subject | FLUID | - |
dc.subject | MRI | - |
dc.title | Rapid Whole-Brain Gray Matter Imaging Using Single-Slab Three-Dimensional Dual-Echo Fast Spin Echo: A Feasibility Study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000416390700005 | - |
dc.identifier.doi | 10.1002/mrm.26910 | - |
dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IN MEDICINE, v.78, no.5, pp.1691 - 1699 | - |
dc.identifier.scopusid | 2-s2.0-85031316745 | - |
dc.citation.endPage | 1699 | - |
dc.citation.startPage | 1691 | - |
dc.citation.title | MAGNETIC RESONANCE IN MEDICINE | - |
dc.citation.volume | 78 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Kim, Eung Yeop | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | magnetic resonance imaging | - |
dc.subject.keywordAuthor | three dimensional | - |
dc.subject.keywordAuthor | spin echo | - |
dc.subject.keywordAuthor | gray matter | - |
dc.subject.keywordAuthor | double-inversion-recovery | - |
dc.subject.keywordPlus | MULTIPLE-SCLEROSIS | - |
dc.subject.keywordPlus | PULSE SEQUENCE | - |
dc.subject.keywordPlus | INVERSION | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | OPTIMIZATION | - |
dc.subject.keywordPlus | SUPPRESSION | - |
dc.subject.keywordPlus | IMAGES | - |
dc.subject.keywordPlus | FLUID | - |
dc.subject.keywordPlus | MRI | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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