ScholarWorks@Gachon

Detailed Information

Cited 17 time in webofscience Cited 21 time in scopus
Metadata Downloads

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of alpha-MSH-stimulated melanogenesis

Full metadata record
DC Field Value Language
dc.contributor.authorJo, Hyeju-
dc.contributor.authorChoi, Minho-
dc.contributor.authorSim, Jaeuk-
dc.contributor.authorViji, Mayavan-
dc.contributor.authorLi, Siyuan-
dc.contributor.authorLee, Young Hee-
dc.contributor.authorKim, Youngsoo-
dc.contributor.authorSeo, Seung-Yong-
dc.contributor.authorZhou, Yuanyuan-
dc.contributor.authorLee, Kiho-
dc.contributor.authorKim, Wun-Jae-
dc.contributor.authorHong, Jin Tae-
dc.contributor.authorLee, Heesoon-
dc.contributor.authorJung, Jae-Kyung-
dc.date.available2020-02-27T17:43:53Z-
dc.date.created2020-02-06-
dc.date.issued2017-08-01-
dc.identifier.issn0960-894X-
dc.identifier.urihttps://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5841-
dc.description.abstractWe have disclosed our effort to develop caffeic acid derivatives as potent and non-toxic inhibitors of alpha-MSH-stimulated melanogenesis to treat pigmentation disorders and skin medication including a cosmetic skin-whitening agent. The SAR studies revealed that cyclohexyl ester and secondary amide derivatives of caffeic acid showed significant inhibitory activities. (C) 2017 Elsevier Ltd. All rights reserved.-
dc.language영어-
dc.language.isoen-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.relation.isPartOfBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.subjectB16 MELANOMA-CELLS-
dc.subjectTYROSINASE INHIBITORS-
dc.subjectDOWN-REGULATION-
dc.subjectSIGNALING PATHWAYS-
dc.subjectSKIN PIGMENTATION-
dc.subjectAGENTS-
dc.subjectMELANOCYTES-
dc.subjectDISCOVERY-
dc.subjectESTER-
dc.titleSynthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of alpha-MSH-stimulated melanogenesis-
dc.typeArticle-
dc.type.rimsART-
dc.description.journalClass1-
dc.identifier.wosid000405106500030-
dc.identifier.doi10.1016/j.bmcl.2017.06.011-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.27, no.15, pp.3374 - 3377-
dc.identifier.scopusid2-s2.0-85020433915-
dc.citation.endPage3377-
dc.citation.startPage3374-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume27-
dc.citation.number15-
dc.contributor.affiliatedAuthorSeo, Seung-Yong-
dc.type.docTypeArticle-
dc.subject.keywordAuthorCaffeic acid-
dc.subject.keywordAuthorMelanogenesis-
dc.subject.keywordAuthoralpha-MSH-
dc.subject.keywordAuthorCaffeamide-
dc.subject.keywordAuthorSkin whitening-
dc.subject.keywordPlusB16 MELANOMA-CELLS-
dc.subject.keywordPlusTYROSINASE INHIBITORS-
dc.subject.keywordPlusDOWN-REGULATION-
dc.subject.keywordPlusSIGNALING PATHWAYS-
dc.subject.keywordPlusSKIN PIGMENTATION-
dc.subject.keywordPlusAGENTS-
dc.subject.keywordPlusMELANOCYTES-
dc.subject.keywordPlusDISCOVERY-
dc.subject.keywordPlusESTER-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Files in This Item
There are no files associated with this item.
Appears in
Collections
약학대학 > 약학과 > 1. Journal Articles
Show simple item record

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Seo, Seung Yong photo

Seo, Seung Yong
Pharmacy (Dept.of Pharmacy)
Read more

Altmetrics

Total Views & Downloads

STATISTICS
Total View :4,148,097
Today View :9,893

RSS_1.0 RSS_2.0 ATOM_1.0

CONTACT US

1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114

COPYRIGHT 2020 Gachon University All Rights Reserved.

Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.

BROWSE

한국어