AlCl3-Mediated Synthesis of 4-Aryl-2-quinolone-3-carboxylates
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yang, Seung-Hye | - |
dc.contributor.author | Jo, Seohyun | - |
dc.contributor.author | Shin, Dongyun | - |
dc.date.available | 2020-02-27T17:43:56Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 0936-5214 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5846 | - |
dc.description.abstract | 4-Aryl-2-quinolones are important skeletons from both chemical and medicinal viewpoints. We herein report the development of an efficient synthetic method for 3-substituted 4-aryl-2-quinolones. The key reaction in this process involves an AlCl3-mediated intramolecular cyclization of substituted 2-(carbamoyl)-3-phenylacrylates, with optimized reaction conditions of 2.0 equivalents of AlCl3, nitrobenzene, 80 degrees C, and 3 hours. The chemical yields of cyclization were found to be sensitive to all reaction conditions. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | GEORG THIEME VERLAG KG | - |
dc.relation.isPartOf | SYNLETT | - |
dc.subject | CELL-CYCLE ARREST | - |
dc.subject | BOND FORMATION | - |
dc.subject | IN-VITRO | - |
dc.subject | DERIVATIVES | - |
dc.subject | 2-QUINOLONES | - |
dc.subject | DAURINOL | - |
dc.subject | CANCER | - |
dc.subject | ROUTE | - |
dc.subject | QUINOLONES | - |
dc.subject | CHEMISTRY | - |
dc.title | AlCl3-Mediated Synthesis of 4-Aryl-2-quinolone-3-carboxylates | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000408092200023 | - |
dc.identifier.doi | 10.1055/s-0036-1588798 | - |
dc.identifier.bibliographicCitation | SYNLETT, v.28, no.13, pp.1614 - 1619 | - |
dc.identifier.scopusid | 2-s2.0-85018769124 | - |
dc.citation.endPage | 1619 | - |
dc.citation.startPage | 1614 | - |
dc.citation.title | SYNLETT | - |
dc.citation.volume | 28 | - |
dc.citation.number | 13 | - |
dc.contributor.affiliatedAuthor | Yang, Seung-Hye | - |
dc.contributor.affiliatedAuthor | Jo, Seohyun | - |
dc.contributor.affiliatedAuthor | Shin, Dongyun | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | 2-quinolone | - |
dc.subject.keywordAuthor | Lewis acid | - |
dc.subject.keywordAuthor | intramolecular | - |
dc.subject.keywordAuthor | cyclization | - |
dc.subject.keywordAuthor | oxidation | - |
dc.subject.keywordPlus | CELL-CYCLE ARREST | - |
dc.subject.keywordPlus | BOND FORMATION | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | 2-QUINOLONES | - |
dc.subject.keywordPlus | DAURINOL | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | ROUTE | - |
dc.subject.keywordPlus | QUINOLONES | - |
dc.subject.keywordPlus | CHEMISTRY | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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