Cytology-Ultrasonography Risk-Stratification Scoring System Based on Fine-Needle Aspiration Cytology and the Korean-Thyroid Imaging Reporting and Data System
DC Field | Value | Language |
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dc.contributor.author | Hong, Min Ji | - |
dc.contributor.author | Na, Dong Gyu | - |
dc.contributor.author | Baek, Jung Hwan | - |
dc.contributor.author | Sung, Jin Yong | - |
dc.contributor.author | Kim, Ji-Hoon | - |
dc.date.available | 2020-02-27T18:41:02Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-07 | - |
dc.identifier.issn | 1050-7256 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/5938 | - |
dc.description.abstract | Background: The malignancy risk of a cytology diagnosis may depend on the ultrasonography (US) patterns of thyroid nodules, and management should be determined by the combined malignancy risk of fine-needle aspiration (FNA) cytology and US patterns. This study was performed to develop a clinically applicable cytology-ultrasonography (CU) scoring system for malignancy risk stratification based on FNA cytology and US patterns, according to the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS). Methods: This retrospective Institutional Review Board-approved study included 1651 thyroid nodules (1cm) with final diagnoses. The malignancy risk was assessed of the combined results of FNA cytology and the K-TIRADS for the development of the CU system. The interaction between FNA cytology and US pattern (K-TIRADS) in the malignancy risk of nodules was investigated by using a binominal test. Results: The malignancy risk of nodules could be stratified into four CU scores (very low risk, <3%; low risk, 3%, <30%; high risk, 30%, <90%; very high risk, 90%). In nodules with non-diagnostic, benign, and atypia of undetermined significance/follicular lesion of undetermined significance cytology results, low-suspicion US pattern (K-TIRADS 3) significantly decreased the malignancy risk of nodules (p=0.003, 0.013, and 0.027, respectively), and a high-suspicion US pattern (K-TIRADS 5) significantly increased the malignancy risk of nodules (p0.001). A Bethesda 1 or 4 cytology result did not significantly change the malignancy risk of any K-TIRADS (p0.518 and p0.137, respectively). A Bethesda 2 cytology result decreased and a Bethesda 5 or 6 cytology result increased the malignancy risk of K-TIRADS 3, 4, and 5 (p0.001). A Bethesda 3 cytology result increased the malignancy risk of K-TIRADS 3 and 4 (p<0.001 and p=0.024, respectively). Conclusion: The malignancy risk of thyroid nodules can be stratified by the CU risk-stratification system, based on FNA cytology and the K-TIRADS. The proposed CU scoring system may be helpful in the management of thyroid nodules after FNA. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.relation.isPartOf | THYROID | - |
dc.subject | CATEGORY III AUS/FLUS | - |
dc.subject | UNDETERMINED SIGNIFICANCE | - |
dc.subject | BETHESDA SYSTEM | - |
dc.subject | FOLLICULAR NEOPLASM | - |
dc.subject | MALIGNANCY RATE | - |
dc.subject | ASSOCIATION GUIDELINES | - |
dc.subject | CONSENSUS STATEMENT | - |
dc.subject | NODULES | - |
dc.subject | ULTRASOUND | - |
dc.subject | MANAGEMENT | - |
dc.title | Cytology-Ultrasonography Risk-Stratification Scoring System Based on Fine-Needle Aspiration Cytology and the Korean-Thyroid Imaging Reporting and Data System | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000404987500012 | - |
dc.identifier.doi | 10.1089/thy.2016.0603 | - |
dc.identifier.bibliographicCitation | THYROID, v.27, no.7, pp.953 - 959 | - |
dc.identifier.scopusid | 2-s2.0-85022186964 | - |
dc.citation.endPage | 959 | - |
dc.citation.startPage | 953 | - |
dc.citation.title | THYROID | - |
dc.citation.volume | 27 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | Hong, Min Ji | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | thyroid | - |
dc.subject.keywordAuthor | ultrasonography | - |
dc.subject.keywordAuthor | biopsy | - |
dc.subject.keywordAuthor | needle aspiration | - |
dc.subject.keywordAuthor | cytology | - |
dc.subject.keywordPlus | CATEGORY III AUS/FLUS | - |
dc.subject.keywordPlus | UNDETERMINED SIGNIFICANCE | - |
dc.subject.keywordPlus | BETHESDA SYSTEM | - |
dc.subject.keywordPlus | FOLLICULAR NEOPLASM | - |
dc.subject.keywordPlus | MALIGNANCY RATE | - |
dc.subject.keywordPlus | ASSOCIATION GUIDELINES | - |
dc.subject.keywordPlus | CONSENSUS STATEMENT | - |
dc.subject.keywordPlus | NODULES | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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