Phenolic Glycosides from Capsella bursa-pastoris (L.) Medik and Their Anti-Inflammatory Activity
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cha, Joon Min | - |
dc.contributor.author | Suh, Won Se | - |
dc.contributor.author | Lee, Tae Hyun | - |
dc.contributor.author | Subedi, Lalita | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Lee, Kang Ro | - |
dc.date.available | 2020-02-27T18:43:00Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6094 | - |
dc.description.abstract | A new sesquilignan glycoside 1, together with seven known phenolic glycosides 2-8 were isolated from the aerial parts of Capsella bursa-pastoris. The chemical structure of the new compound 1 was elucidated by extensive nuclear magnetic resonance (NMR) data (H-1- and C-13-NMR, H-1-H-1 correlation spectroscopy (H-1-H-1 COSY), heteronuclear single-quantum correlation (HSQC), heteronuclear multiple bond correlation (HMBC), and nuclear overhauser effect spectroscopy (NOESY)) and HR-FABMS analysis. The anti-inflammatory effects of 1-8 were evaluated in lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cells. Compounds 4 and 7 exhibited moderate inhibitory effects on nitric oxide production in LPS-activated BV-2 cells, with IC50 values of 17.80 and 27.91 mu M, respectively. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | MOLECULES | - |
dc.subject | NITRIC-OXIDE | - |
dc.subject | CONSTITUENTS | - |
dc.subject | GLUCOSIDES | - |
dc.subject | CELLS | - |
dc.subject | PURSE | - |
dc.title | Phenolic Glycosides from Capsella bursa-pastoris (L.) Medik and Their Anti-Inflammatory Activity | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000404642100165 | - |
dc.identifier.doi | 10.3390/molecules22061023 | - |
dc.identifier.bibliographicCitation | MOLECULES, v.22, no.6 | - |
dc.identifier.scopusid | 2-s2.0-85021166455 | - |
dc.citation.title | MOLECULES | - |
dc.citation.volume | 22 | - |
dc.citation.number | 6 | - |
dc.contributor.affiliatedAuthor | Subedi, Lalita | - |
dc.contributor.affiliatedAuthor | Kim, Sun Yeou | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Capsella bursa-pastoris | - |
dc.subject.keywordAuthor | Cruciferae | - |
dc.subject.keywordAuthor | sesquilignan glycoside | - |
dc.subject.keywordAuthor | anti-inflammatory | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | GLUCOSIDES | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | PURSE | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.