Molecular Testing of Lung Cancers
DC Field | Value | Language |
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dc.contributor.author | Shim, Hyo Sup | - |
dc.contributor.author | Choi, Yoon-La | - |
dc.contributor.author | Kim, Lucia | - |
dc.contributor.author | Chang, Sunhee | - |
dc.contributor.author | Kim, Wan-Seop | - |
dc.contributor.author | Roh, Mee Sook | - |
dc.contributor.author | Kim, Tae-Jung | - |
dc.contributor.author | Ha, Seung Yeon | - |
dc.contributor.author | Chung, Jin-Haeng | - |
dc.contributor.author | Jang, Se Jin | - |
dc.contributor.author | Lee, Geon Kook | - |
dc.date.available | 2020-02-27T18:43:45Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 2383-7837 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6146 | - |
dc.description.abstract | Targeted therapies guided by molecular diagnostics have become a standard treatment of lung cancer. Epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements are currently used as the best predictive biomarkers for EGFR tyrosine kinase inhibitors and ALK inhibitors, respectively. Besides EGFR and ALK, the list of druggable genetic alterations has been growing, including ROS1 rearrangements, RET rearrangements, and MET alterations. In this situation, pathologists should carefully manage clinical samples for molecular testing and should do their best to quickly and accurately identify patients who will benefit from precision therapeutics. Here, we grouped molecular biomarkers of lung cancers into three categories-mutations, gene rearrangements, and amplifications-and propose expanded guidelines on molecular testing of lung cancers. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC PATHOLOGISTS | - |
dc.relation.isPartOf | JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE | - |
dc.subject | GENE COPY NUMBER | - |
dc.subject | TYROSINE KINASE INHIBITORS | - |
dc.subject | FACTOR RECEPTOR INHIBITORS | - |
dc.subject | MULTICENTER PHASE-2 TRIAL | - |
dc.subject | POLYMERASE-CHAIN-REACTION | - |
dc.subject | HARBORING BRAF MUTATIONS | - |
dc.subject | IN-SITU HYBRIDIZATION | - |
dc.subject | ACQUIRED-RESISTANCE | - |
dc.subject | EGFR MUTATIONS | - |
dc.subject | OPEN-LABEL | - |
dc.title | Molecular Testing of Lung Cancers | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000401278900004 | - |
dc.identifier.doi | 10.4132/jptm.2017.04.10 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, v.51, no.3, pp.242 - 254 | - |
dc.identifier.kciid | ART002224111 | - |
dc.identifier.scopusid | 2-s2.0-85019869649 | - |
dc.citation.endPage | 254 | - |
dc.citation.startPage | 242 | - |
dc.citation.title | JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE | - |
dc.citation.volume | 51 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Ha, Seung Yeon | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | Lung neoplasms | - |
dc.subject.keywordAuthor | Molecular testing | - |
dc.subject.keywordAuthor | Guideline | - |
dc.subject.keywordAuthor | Precision medicine | - |
dc.subject.keywordPlus | GENE COPY NUMBER | - |
dc.subject.keywordPlus | TYROSINE KINASE INHIBITORS | - |
dc.subject.keywordPlus | FACTOR RECEPTOR INHIBITORS | - |
dc.subject.keywordPlus | MULTICENTER PHASE-2 TRIAL | - |
dc.subject.keywordPlus | POLYMERASE-CHAIN-REACTION | - |
dc.subject.keywordPlus | HARBORING BRAF MUTATIONS | - |
dc.subject.keywordPlus | IN-SITU HYBRIDIZATION | - |
dc.subject.keywordPlus | ACQUIRED-RESISTANCE | - |
dc.subject.keywordPlus | EGFR MUTATIONS | - |
dc.subject.keywordPlus | OPEN-LABEL | - |
dc.relation.journalResearchArea | Pathology | - |
dc.relation.journalWebOfScienceCategory | Pathology | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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