Fabrication and tissue engineering application of a 3D PPF/DEF scaffold using Blu-ray based 3D printing system
DC Field | Value | Language |
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dc.contributor.author | Kim, Jae-Hun | - |
dc.contributor.author | Lee, Jin Woo | - |
dc.contributor.author | Yun, Won-Soo | - |
dc.date.available | 2020-02-27T18:44:17Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2017-05 | - |
dc.identifier.issn | 1738-494X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6186 | - |
dc.description.abstract | Micro-stereolithography (MSTL) among various 3D printing technologies reaches high resolution by using a focused laser beam, and therefore it can be used to fabricate objects that have feature sizes of tens to hundreds of micrometers. To fabricate a scaffold for the tissue engineering, we used a Blu-ray based MSTL system which is simpler and more compact than the conventional MSTL system. We selected a biodegradable photopolymer, Poly (propylene fumarate)/diethyl fumarate (PPF/DEF), as the construction material, and progressed post-curing to strengthen the fabricated scaffold. We seeded MC3T3-E1 pre-osteoblasts on the fabricated PPF/DEF 3D scaffolds and cultured them in a multi-stimulus bioreactor system which mimics the in-vivo shear flow environment and simultaneously supplies a magnetic field to improve cell proliferation. A cell culture result showed the superiority of combining our bioreactor system with the PPF/DEF 3D scaffold. The combination of 3D scaffold fabricated by Blu-ray based MSTL and a multi-stimulus bioreactor system may be a valuable tool for bone tissue regeneration. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC MECHANICAL ENGINEERS | - |
dc.relation.isPartOf | JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY | - |
dc.subject | MECHANICAL-PROPERTIES | - |
dc.subject | CELL-PROLIFERATION | - |
dc.subject | MAGNETIC-FIELDS | - |
dc.subject | DRUG-DELIVERY | - |
dc.subject | IN-VITRO | - |
dc.subject | BONE | - |
dc.subject | STEREOLITHOGRAPHY | - |
dc.subject | ANGIOGENESIS | - |
dc.subject | DEGRADATION | - |
dc.subject | CONSTRUCTS | - |
dc.title | Fabrication and tissue engineering application of a 3D PPF/DEF scaffold using Blu-ray based 3D printing system | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000401709100057 | - |
dc.identifier.doi | 10.1007/s12206-017-0456-y | - |
dc.identifier.bibliographicCitation | JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY, v.31, no.5, pp.2581 - 2587 | - |
dc.identifier.kciid | ART002221521 | - |
dc.identifier.scopusid | 2-s2.0-85019564078 | - |
dc.citation.endPage | 2587 | - |
dc.citation.startPage | 2581 | - |
dc.citation.title | JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY | - |
dc.citation.volume | 31 | - |
dc.citation.number | 5 | - |
dc.contributor.affiliatedAuthor | Lee, Jin Woo | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | 3D printing | - |
dc.subject.keywordAuthor | Blu-ray | - |
dc.subject.keywordAuthor | Scaffold | - |
dc.subject.keywordAuthor | Bioreactor | - |
dc.subject.keywordAuthor | Multi-stimuli | - |
dc.subject.keywordPlus | MECHANICAL-PROPERTIES | - |
dc.subject.keywordPlus | CELL-PROLIFERATION | - |
dc.subject.keywordPlus | MAGNETIC-FIELDS | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | STEREOLITHOGRAPHY | - |
dc.subject.keywordPlus | ANGIOGENESIS | - |
dc.subject.keywordPlus | DEGRADATION | - |
dc.subject.keywordPlus | CONSTRUCTS | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Engineering, Mechanical | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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