Safety and effectiveness of endobiliary radiofrequency ablation according to the different power and target temperature in a swine model
DC Field | Value | Language |
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dc.contributor.author | Cho, Jae Hee | - |
dc.contributor.author | Lee, Kwang Hyuck | - |
dc.contributor.author | Kim, Joon Mee | - |
dc.contributor.author | Kim, Yeon Suk | - |
dc.contributor.author | Lee, Don Haeng | - |
dc.contributor.author | Jeong, Seok | - |
dc.date.available | 2020-02-27T19:43:53Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017-02 | - |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6420 | - |
dc.description.abstract | Background and AimEndobiliary radiofrequency ablation (EB-RFA) is a new endoscopic palliation and adjunctive tool. Although EB-RFA is performed worldwide, a possibility of iatrogenic thermal injury leading to perforation or bleeding still remains. Therefore, we aimed to assess the effects of thermal and coagulation injury after in vivo EB-RFA using a new catheter with a temperature sensor in a swine model. MethodsTwelve mini pigs were divided into four groups according to power (33mm 10W electrode vs. 18mm 7W electrode) and RFA target temperature (75 degrees C vs. 80 degrees C). All mini pigs underwent endoscopic retrograde cholangiography and target temperature controlled EB-RFA for 120s. Additional cholangiogram was taken immediately after RFA, and all pigs were sacrificed after 24h to assess the macroscopic/microscopic RFA injury. ResultsMicroscopic maximal injury depth and ablation area of EB-RFA using a 33-mm 10W RFA electrode were significantly deeper and larger than those of EB-RFA using an 18-mm 7W electrode (median; 2.7 vs. 2.1mm, P=0.004, 48.9 vs. 36.2mm(2), P=0.016). However, there were no significant differences in microscopic ablation parameters between two different RFA target temperatures (75 degrees C vs. 80 degrees C). In addition, a post-RFA cholangiogram and assessment of the resected specimen at 24h after the RFA showed no adverse events such as perforation or bleeding. ConclusionsEB-RFA using a temperature controlled RFA catheter successfully ablates the bile duct wall without adverse events in a swine model. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.subject | MALIGNANT BILIARY OBSTRUCTION | - |
dc.subject | CATHETER | - |
dc.subject | TRIAL | - |
dc.title | Safety and effectiveness of endobiliary radiofrequency ablation according to the different power and target temperature in a swine model | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000395649200034 | - |
dc.identifier.doi | 10.1111/jgh.13472 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, v.32, no.2, pp.521 - 526 | - |
dc.identifier.scopusid | 2-s2.0-85013290454 | - |
dc.citation.endPage | 526 | - |
dc.citation.startPage | 521 | - |
dc.citation.title | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.citation.volume | 32 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | Cho, Jae Hee | - |
dc.contributor.affiliatedAuthor | Kim, Yeon Suk | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | animal experiments | - |
dc.subject.keywordAuthor | biliary neoplasms | - |
dc.subject.keywordAuthor | endoscopic retrograde cholangiography | - |
dc.subject.keywordAuthor | radiofrequency catheter ablation | - |
dc.subject.keywordPlus | MALIGNANT BILIARY OBSTRUCTION | - |
dc.subject.keywordPlus | CATHETER | - |
dc.subject.keywordPlus | TRIAL | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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