The Predictive Value of Tumor Size, Volume, and Markers During Radiation Therapy in Patients With Cervical Cancer
DC Field | Value | Language |
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dc.contributor.author | Lee, Kyu Chan | - |
dc.contributor.author | Kim, Hun Jung | - |
dc.contributor.author | Sung, KiHoon | - |
dc.contributor.author | Choi, Young Eun | - |
dc.contributor.author | Lee, Seok Ho | - |
dc.contributor.author | Lim, Soyi | - |
dc.contributor.author | Lee, Kwang Beom | - |
dc.contributor.author | Shin, Jin Woo | - |
dc.contributor.author | Park, Chan Yong | - |
dc.contributor.author | Kim, Young Saing | - |
dc.contributor.author | Sym, Sun Jin | - |
dc.contributor.author | Shim, Young Sup | - |
dc.contributor.author | Choi, Seung Joon | - |
dc.date.available | 2020-02-27T19:45:03Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 1048-891X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6512 | - |
dc.description.abstract | Objectives: We investigated the prognostic significance of changes in primary tumor volume and serum squamous cell carcinoma antigen (SCC-ag) levels during radiation therapy (RT) in patients with cervical cancer. Methods: We conducted a review of 40 patients treated with RT. All patients received external beam RT and intracavitary brachytherapy. The primary tumor volume and squamous cell carcinoma antigen levels were measured pre-RT and mid-RT. Overall survival (OS) and progression free survival (PFS) were estimated, and possible prognostic factors for survival were analyzed. Results: The correlation coefficient between primary tumor volume reduction rate (pTVRR) and serum squamous cell carcinoma antigen reduction rate in all patients was 0.550 (P < 0.001). In univariate analysis, stage more than II (P<0.001), pre-RT pTV of 55 cm(3) or more (P = 0.05), mid-RT tumor size of 4 cm or more (P = 0.004), and pTVRR of 90% or less (P = 0.031) were significant unfavorable prognostic factors for PFS, whereas stage (P = 0.009) was the only significant prognostic factor for OS. Multivariable analysis revealed that none of these factors were independently associated with PFS or OS. Conclusions: There was a significant correlation between pTVRR and squamous cell carcinoma antigen reduction rate. Our findings indicate that the tumor parameters such as pre-RTpTV, mid-RT tumor size, and pTVRR are associated with PFS in women with cervical cancer. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | - |
dc.title | The Predictive Value of Tumor Size, Volume, and Markers During Radiation Therapy in Patients With Cervical Cancer | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000391946600019 | - |
dc.identifier.doi | 10.1097/IGC.0000000000000837 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, v.27, no.1, pp.123 - 130 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85010047133 | - |
dc.citation.endPage | 130 | - |
dc.citation.startPage | 123 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | - |
dc.citation.volume | 27 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Lee, Kyu Chan | - |
dc.contributor.affiliatedAuthor | Sung, KiHoon | - |
dc.contributor.affiliatedAuthor | Choi, Young Eun | - |
dc.contributor.affiliatedAuthor | Lee, Seok Ho | - |
dc.contributor.affiliatedAuthor | Lim, Soyi | - |
dc.contributor.affiliatedAuthor | Lee, Kwang Beom | - |
dc.contributor.affiliatedAuthor | Shin, Jin Woo | - |
dc.contributor.affiliatedAuthor | Park, Chan Yong | - |
dc.contributor.affiliatedAuthor | Kim, Young Saing | - |
dc.contributor.affiliatedAuthor | Sym, Sun Jin | - |
dc.contributor.affiliatedAuthor | Shim, Young Sup | - |
dc.contributor.affiliatedAuthor | Choi, Seung Joon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Cervix cancer | - |
dc.subject.keywordAuthor | Radiation therapy | - |
dc.subject.keywordAuthor | Tumor volume | - |
dc.subject.keywordAuthor | Squamous cell carcinoma antigen | - |
dc.subject.keywordPlus | SQUAMOUS-CELL CARCINOMA | - |
dc.subject.keywordPlus | UTERINE CERVIX | - |
dc.subject.keywordPlus | ANTIGEN LEVELS | - |
dc.subject.keywordPlus | PROGNOSTIC-SIGNIFICANCE | - |
dc.subject.keywordPlus | SERUM | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | CHEMORADIOTHERAPY | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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