Clinical Outcomes according to the Achievement of Target Low Density Lipoprotein-Cholesterol in Patients with Acute Myocardial Infarction
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ahn, Taehoon | - |
dc.contributor.author | Suh, Soon Yong | - |
dc.contributor.author | Lee, Kyounghoon | - |
dc.contributor.author | Kang, Woong Chol | - |
dc.contributor.author | Han, Seung Hwan | - |
dc.contributor.author | Ahn, Youngkeun | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.date.available | 2020-02-27T19:45:12Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 1738-5520 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6519 | - |
dc.description.abstract | Background and Objectives:The clinical outcome of patient with an acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI), with or without achievement of target low density lipoprotein-cholesterol (LDL-C), has little known information. This study investigated if target LDL-C level (below 70 mg/dL) achievements in patients with AMI showed better clinical outcomes or not. Subjects and Methods: Between May 2008 and September 2012, this study enrolled 13473 AMI patients in a large-scale, prospective, multicenter Korean Myocardial Infarction (KorMI) registry. 12720 patients survived and 6746 patients completed a 1-year clinical follow up. Among them 3315 patients received serial lipid profile follow-ups. Propensity score matching was applied to adjust for differences in clinical baseline and angiographic characteristics, producing a total of 1292 patients (646 target LDL-C achievers vs. 646 non-achievers). The primary end point was the composite of a 1-year major adverse cardiac event (MACE) including cardiac death, recurrent myocardial infarction (MI), target lesion revascularization (TLR) and coronary artery bypass grafting. Results: After propensity score matching, baseline clinical and angiographic characteristics were similar between the two groups. Clinical outcomes of the propensity score matched patients who showed no significant differences in cardiac death (0.5% vs. 0.5%, p=1.000), recurrent MI (1.1% vs. 0.8%, p=0.562),.TLR (5.00% vs. 4.5%, p=0.649), MACEs (6.5% vs. 5.9%, p=0.644) and stent thrombosis (2.5% vs. 1.9%, p=0.560). Conclusion: In this propensity-matched comparison, AMI patients undergoing PCI with a target LDL-C (below 70 mg/dL) achievement did not show better clinical outcomes. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC CARDIOLOGY | - |
dc.relation.isPartOf | KOREAN CIRCULATION JOURNAL | - |
dc.subject | ACUTE CORONARY SYNDROMES | - |
dc.subject | STATIN THERAPY | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.subject | SERUM-CHOLESTEROL | - |
dc.subject | JAPANESE PATIENTS | - |
dc.subject | METAANALYSIS | - |
dc.subject | RISK | - |
dc.subject | ATORVASTATIN | - |
dc.subject | PREVENTION | - |
dc.subject | REDUCTION | - |
dc.title | Clinical Outcomes according to the Achievement of Target Low Density Lipoprotein-Cholesterol in Patients with Acute Myocardial Infarction | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000392558200007 | - |
dc.identifier.doi | 10.4070/kcj.2015.0266 | - |
dc.identifier.bibliographicCitation | KOREAN CIRCULATION JOURNAL, v.47, no.1, pp.31 - 35 | - |
dc.identifier.kciid | ART002193234 | - |
dc.identifier.scopusid | 2-s2.0-85009084223 | - |
dc.citation.endPage | 35 | - |
dc.citation.startPage | 31 | - |
dc.citation.title | KOREAN CIRCULATION JOURNAL | - |
dc.citation.volume | 47 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Ahn, Taehoon | - |
dc.contributor.affiliatedAuthor | Suh, Soon Yong | - |
dc.contributor.affiliatedAuthor | Lee, Kyounghoon | - |
dc.contributor.affiliatedAuthor | Kang, Woong Chol | - |
dc.contributor.affiliatedAuthor | Han, Seung Hwan | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Myocardial infarction | - |
dc.subject.keywordAuthor | Low density lipoprotein-cholesterol | - |
dc.subject.keywordAuthor | Treatment outcome | - |
dc.subject.keywordPlus | ACUTE CORONARY SYNDROMES | - |
dc.subject.keywordPlus | STATIN THERAPY | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | SERUM-CHOLESTEROL | - |
dc.subject.keywordPlus | JAPANESE PATIENTS | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | ATORVASTATIN | - |
dc.subject.keywordPlus | PREVENTION | - |
dc.subject.keywordPlus | REDUCTION | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.