Effect of number of retrieved lymph nodes on prognosis in FIGO stage IB-IIA cervical cancer patients treated with primary radical surgery
DC Field | Value | Language |
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dc.contributor.author | Lim, Soyi | - |
dc.contributor.author | Cho, Kyungjoo | - |
dc.contributor.author | Lee, Seungho | - |
dc.contributor.author | Lee, Kwangbeom | - |
dc.contributor.author | Shin, Jinwoo | - |
dc.contributor.author | Chung, Donghae | - |
dc.contributor.author | Park, Chanyong | - |
dc.date.available | 2020-02-27T19:45:20Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 1341-8076 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6527 | - |
dc.description.abstract | AimIn the treatment of cervical cancer, the extent of lymphadenectomy is a matter of debate. The goal of the current study was to examine the question of whether the number of retrieved lymph nodes (RLN) can influence survival of patients with early stage cervical cancer. MethodsThe medical records of 180 FIGO stage IB-IIA cervical cancer patients treated with primary radical surgery were reviewed. Patients were divided into two groups: those with 40 RLN and those with > 40 RLN. Patients were also assigned to either the bulky (tumor size>4 cm) cervical cancer group or the non-bulky (tumor size4 cm) cervical cancer group. ResultsThe number of RLN had a statistically significant effect on both disease-free survival (P = 0.04) and overall survival (P = 0.02) of all patients. Patients with>40 RLN had better prognoses than those with40 RLN. In the bulky cervical cancer group, the number of RLN was an independent prognostic factor. In multivariate analysis for the bulky cervical cancer group, >40 RLN had a significant positive effect on disease-free survival (adjusted hazard ratio, 0.36; 95% confidence interval, 0.13-0.97) and overall survival (adjusted hazard ratio, 0.23; 95% confidence interval, 0.06-0.90). However, number of RLN was not an independent prognostic factor in the non-bulky cervical cancer group. ConclusionsA more extensive lymphadenectomy increased the survival of bulky cervical cancer patients. This finding may be helpful in determining surgical extent before surgery for cervical cancer. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.relation.isPartOf | JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | - |
dc.subject | EMISSION-TOMOGRAPHY | - |
dc.subject | SINGLE INSTITUTION | - |
dc.subject | QUALITY-CONTROL | - |
dc.subject | LYMPHADENECTOMY | - |
dc.subject | HYSTERECTOMY | - |
dc.subject | CARCINOMA | - |
dc.subject | MALIGNANCIES | - |
dc.subject | RADIOTHERAPY | - |
dc.subject | METAANALYSIS | - |
dc.subject | MORTALITY | - |
dc.title | Effect of number of retrieved lymph nodes on prognosis in FIGO stage IB-IIA cervical cancer patients treated with primary radical surgery | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000393803900031 | - |
dc.identifier.doi | 10.1111/jog.13171 | - |
dc.identifier.bibliographicCitation | JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, v.43, no.1, pp.211 - 219 | - |
dc.identifier.scopusid | 2-s2.0-85003486099 | - |
dc.citation.endPage | 219 | - |
dc.citation.startPage | 211 | - |
dc.citation.title | JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | - |
dc.citation.volume | 43 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Lim, Soyi | - |
dc.contributor.affiliatedAuthor | Cho, Kyungjoo | - |
dc.contributor.affiliatedAuthor | Lee, Seungho | - |
dc.contributor.affiliatedAuthor | Lee, Kwangbeom | - |
dc.contributor.affiliatedAuthor | Shin, Jinwoo | - |
dc.contributor.affiliatedAuthor | Chung, Donghae | - |
dc.contributor.affiliatedAuthor | Park, Chanyong | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | lymph node excision | - |
dc.subject.keywordAuthor | lymph nodes | - |
dc.subject.keywordAuthor | prognosis | - |
dc.subject.keywordAuthor | uterine cervical neoplasms | - |
dc.subject.keywordPlus | EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | SINGLE INSTITUTION | - |
dc.subject.keywordPlus | QUALITY-CONTROL | - |
dc.subject.keywordPlus | LYMPHADENECTOMY | - |
dc.subject.keywordPlus | HYSTERECTOMY | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | MALIGNANCIES | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.relation.journalResearchArea | Obstetrics & Gynecology | - |
dc.relation.journalWebOfScienceCategory | Obstetrics & Gynecology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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