Skull Metastasis of Gastric Gastrointestinal Stromal Tumor Successfully Managed by Surgery
- Authors
- Park, Inkeun; Chung, Dong Hae; Yoo, Chan Jong; Shin, Dong Bok
- Issue Date
- Jan-2017
- Publisher
- KOREAN NEUROSURGICAL SOC
- Keywords
- Gastrointestinal stromal tumor; Skull metastasis; Metastasectomy; Target therapy; Multidisciplinary treatment
- Citation
- JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, v.60, no.1, pp.94 - 97
- Journal Title
- JOURNAL OF KOREAN NEUROSURGICAL SOCIETY
- Volume
- 60
- Number
- 1
- Start Page
- 94
- End Page
- 97
- URI
- https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/6537
- DOI
- 10.3340/jkns.2014.0506.007
- ISSN
- 2005-3711
- Abstract
- Gastrointestinal stromal tumors (GISTs) are rare, but are the most common mesenchymal neoplasm of the gastrointestinal tract. The most common sites of metastasis are liver and peritoneum, while bone metastasis is rare. We report on a patient with skull metastasis after seven years of treatment with imatinib for metastatic GIST. She underwent metastasectomy consisting of craniectomy with excision of the mass, and cranioplasty and continued treatment with imatinib and sunitinib, without evidence of cranial recurrence. She died of pneumonia sepsis one year after metastasectomy. Skull metastasis of GIST is a very rare presentation, and an aggressive multidisciplinary approach should be considered whenever possible.
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