梔子의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경희 | - |
dc.contributor.author | 김선미 | - |
dc.contributor.author | 신승훈 | - |
dc.contributor.author | 이영종 | - |
dc.contributor.author | 백완숙 | - |
dc.date.available | 2020-02-27T22:41:10Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1229-1765 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7162 | - |
dc.description.abstract | Objectives : Gardeniae Fructus is a ripe fruit of Gardenia jasminoides Ellis, which has been used as traditional medicines for anti-inflammatory, diuretic, antipyretic, and antibacterial activity. The aim of this study was to compare of Gardeniae Fructus in South Korea collected during three years according to the standards in monographs of the Korean Pharmacopoeia Eleventh edition (KP11). Methods : 30 items of Gardeniae Fructus from two cultivation regions were classified into dried(n=15) & steamed (n=15) and tested according to the standards in monographs of the KP11. Gardeniae Fructus was carried out identification(comparison of colors, thin layer chromatography), heavy metals, residual pesticides, total ash, and assay registered at KP11. Add to we tested loss on dry, contents of ethanol-soluble extracts, and HPLC profiling. Results : In TLC chromatogram of identification test, the spot of gardenoside and geniposide were observed at Rf value of about 0.3 and 0.5. Heavy metals and residual pesticides met the requirements of the standards for all samples. The results of total ash of each samples are measured maximum 4.87 %. According to HPLC for assay, the samples contain 4.80∼6.10 % of geniposide and 0.45∼1.83 % of gardenoside. Conclusion : We have verified the current specification standard of Gardeniae Fructus and standard that is not set. By the results, it is proposed a new draft of loss on drying and confirmed the content of gardenoside revised. HPLC standard chromatogram of Gardeniae Fructus is proposed. We hope that it will help the standardization of Gardeniae Fructus. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한본초학회 | - |
dc.relation.isPartOf | 대한본초학회지 | - |
dc.title | 梔子의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구 | - |
dc.title.alternative | Quality Monitoring of Specification Standard of Gardeniae Fructus in the Korean Pharmacopoeia and Studies HPLC Standard Chromatogram | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 대한본초학회지, v.32, no.2, pp.97 - 105 | - |
dc.identifier.kciid | ART002206738 | - |
dc.citation.endPage | 105 | - |
dc.citation.startPage | 97 | - |
dc.citation.title | 대한본초학회지 | - |
dc.citation.volume | 32 | - |
dc.citation.number | 2 | - |
dc.contributor.affiliatedAuthor | 이영종 | - |
dc.subject.keywordAuthor | Gardeniae Fructus | - |
dc.subject.keywordAuthor | Quality control | - |
dc.subject.keywordAuthor | Pharmacopoeia | - |
dc.subject.keywordAuthor | Geniposide | - |
dc.subject.keywordAuthor | Gardenoside | - |
dc.description.journalRegisteredClass | kci | - |
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