山楂의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경희 | - |
dc.contributor.author | 김선미 | - |
dc.contributor.author | 이영종 | - |
dc.contributor.author | 백완숙 | - |
dc.date.available | 2020-02-27T22:41:26Z | - |
dc.date.created | 2020-02-12 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1229-1765 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7188 | - |
dc.description.abstract | Objectives : Crataegi Fructus has been used as traditional medicines for more digestion action, amenorrhea due to blood stasis, and hyperlipemia. The aim of this study was to compare of Crataegi Fructus in South Korea collected during three years according to the standards in monographs of the Korean Pharmacopoeia Eleventh edition (KP 11). Methods : Crataegi Fructus was carried out identification test (Qualitative reaction, Thin layer chromatography), heavy metal test, and total ash registered at KP. Add to we tested loss on dry, contents of ethanol-soluble extracts, and HPLC profiling. Results : Identification test (TLC) was on comparing with ursolic acid standard solution in Rf value, all samples showed red purple spot (Rf value 0.9). Ursolic acid spot in Rf value 0.35 showed by changing mobile phase condition. Heavy metals showed contents for Pb, Cd, As, and Hg range of 0.0 ∼ 0.5 ppm, 0.0 ∼ 0.2 ppm, 0.0 ∼ 0.3 ppm, and 0.0 ∼ 0.1 ppm. Loss on drying was ranged from 5.5 to 11.9 %, total ash was between the range 2.7 ∼ 4.0 %. Contents of ethanol-soluble extracts was ranged from 17.8 to 44.9 %. The content of chlorogenic acid was ranged from 0.0 to 0.1 % based on the chlorogenic acid standard curve. Conclusion : We have verified the current specification standard of Crataegi Fructus and standard that is not set. We hope that it will help the standardization of Crataegi Fructus. | - |
dc.language | 한국어 | - |
dc.language.iso | ko | - |
dc.publisher | 대한본초학회 | - |
dc.relation.isPartOf | 대한본초학회지 | - |
dc.title | 山楂의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구 | - |
dc.title.alternative | Quality Monitoring of Specification of Crataegi Fructus in the Korean Pharmacopoeia and Studies HPLC Standard Chromatogram | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 2 | - |
dc.identifier.bibliographicCitation | 대한본초학회지, v.32, no.1, pp.55 - 62 | - |
dc.identifier.kciid | ART002192811 | - |
dc.citation.endPage | 62 | - |
dc.citation.startPage | 55 | - |
dc.citation.title | 대한본초학회지 | - |
dc.citation.volume | 32 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | 이영종 | - |
dc.subject.keywordAuthor | Crataegi Fructus | - |
dc.subject.keywordAuthor | Hawthorn fruit | - |
dc.subject.keywordAuthor | Pharmacopoeia | - |
dc.subject.keywordAuthor | Chlorogenic acid | - |
dc.description.journalRegisteredClass | kci | - |
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