Recent developments in the nanostructured materials functionalized with ruthenium complexes for targeted drug delivery to tumors
DC Field | Value | Language |
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dc.contributor.author | Thangavel, Prakash | - |
dc.contributor.author | Viswanath, Buddolla | - |
dc.contributor.author | Kim, Sanghyo | - |
dc.date.available | 2020-02-27T23:41:15Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1178-2013 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7448 | - |
dc.description.abstract | In recent years, the field of metal-based drugs has been dominated by other existing precious metal drugs, and many researchers have focused their attention on the synthesis of various ruthenium (Ru) complexes due to their potential medical and pharmaceutical applications. The beneficial properties of Ru, which make it a highly promising therapeutic agent, include its variable oxidation states, low toxicity, high selectivity for diseased cells, ligand exchange properties, and the ability to mimic iron binding to biomolecules. In addition, Ru complexes have favorable adsorption properties, along with excellent photochemical and photophysical properties, which make them promising tools for photodynamic therapy. At present, nanostructured materials functionalized with Ru complexes have become an efficient way to administer Ru-based anticancer drugs for cancer treatment. In this review, the recent developments in the nanostructured materials functionalized with Ru complexes for targeted drug delivery to tumors are discussed. In addition, information on "traditional" (ie, non-nanostructured) Ru-based cancer therapies is included in a precise manner. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | DOVE MEDICAL PRESS LTD | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.subject | IN-VITRO CYTOTOXICITY | - |
dc.subject | ANTICANCER ACTIVITY | - |
dc.subject | METAL-COMPLEXES | - |
dc.subject | DNA-BINDING | - |
dc.subject | RU(II) COMPLEXES | - |
dc.subject | REACTIVE OXYGEN | - |
dc.subject | ANTITUMOR | - |
dc.subject | ARENE | - |
dc.subject | POLYPYRIDYL | - |
dc.subject | CARRIER | - |
dc.title | Recent developments in the nanostructured materials functionalized with ruthenium complexes for targeted drug delivery to tumors | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000398663000001 | - |
dc.identifier.doi | 10.2147/IJN.S131304 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF NANOMEDICINE, v.12, pp.2749 - 2758 | - |
dc.identifier.scopusid | 2-s2.0-85017402386 | - |
dc.citation.endPage | 2758 | - |
dc.citation.startPage | 2749 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF NANOMEDICINE | - |
dc.citation.volume | 12 | - |
dc.contributor.affiliatedAuthor | Thangavel, Prakash | - |
dc.contributor.affiliatedAuthor | Viswanath, Buddolla | - |
dc.contributor.affiliatedAuthor | Kim, Sanghyo | - |
dc.type.docType | Review | - |
dc.subject.keywordAuthor | metallodrugs | - |
dc.subject.keywordAuthor | nanotechnology | - |
dc.subject.keywordAuthor | cancer treatment | - |
dc.subject.keywordAuthor | cell apoptosis | - |
dc.subject.keywordAuthor | DNA damage | - |
dc.subject.keywordAuthor | toxicity | - |
dc.subject.keywordPlus | IN-VITRO CYTOTOXICITY | - |
dc.subject.keywordPlus | ANTICANCER ACTIVITY | - |
dc.subject.keywordPlus | METAL-COMPLEXES | - |
dc.subject.keywordPlus | DNA-BINDING | - |
dc.subject.keywordPlus | RU(II) COMPLEXES | - |
dc.subject.keywordPlus | REACTIVE OXYGEN | - |
dc.subject.keywordPlus | ANTITUMOR | - |
dc.subject.keywordPlus | ARENE | - |
dc.subject.keywordPlus | POLYPYRIDYL | - |
dc.subject.keywordPlus | CARRIER | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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