Clinicopathological characteristics of biliary neuroendocrine neoplasms: a multicenter study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Kyong Joo | - |
dc.contributor.author | Cho, Jae Hee | - |
dc.contributor.author | Lee, Sang Hyub | - |
dc.contributor.author | Lee, Kwang Hyuk | - |
dc.contributor.author | Park, Byung Kyu | - |
dc.contributor.author | Lee, Jun Kyu | - |
dc.contributor.author | Woo, Sang Myung | - |
dc.contributor.author | Ryu, Ji Kon | - |
dc.contributor.author | Lee, Jong Kyun | - |
dc.contributor.author | Kim, Yeon Suk | - |
dc.contributor.author | Kim, Jae Woo | - |
dc.contributor.author | Lee, Woo Jin | - |
dc.date.available | 2020-02-27T23:42:10Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0036-5521 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7516 | - |
dc.description.abstract | Objectives: This study assessed the clinicopathological features, therapeutic approaches, and prognosis of patients with biliary neuroendocrine neoplasm (NENs). Materials and methods: Multicenter retrospective study of patients with biliary tract NENs in the gallbladder, the extrahepatic bile duct, or the ampulla of Vater between 2005 and 2014. Results: Total of 43 patients were included in the study. The median age was 62 years (range: 29-84 years) and 58.1% of the patients were male. The tumors occurred in the gallbladder (n = 11), the extrahepatic bile duct (n = 5) or the ampulla of Vater (n = 27). The liver was the most common metastatic site. Based on the 2010 World Health Organization classification, more patients with gallbladder NENs (11/11 (100%)) had neuroendocrine carcinoma G3 than those with NENs in the ampulla of Vater (10/27 (37.1%)). The median progression free survival time (39.3 vs 5.1 months, p = 0.001) and median overall survival time (46.9 vs 7.9 months, p<0.001) were significantly longer in patients with ampulla of Vater NENs than gallbladder NENs. A 2010 World Health Organization classification of neuroendocrine carcinoma G3 was independently related to poor overall survival (hazard ratio (HR), 27.1; 95% confidence intervals (CI), 2.81-260.68; p = 0.004). Conclusion: The 2010 World Health Organization classification of neuroendocrine carcinoma G3 was the only factor related to poor prognosis in patients with biliary neuroendocrine neoplasms. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.relation.isPartOf | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | - |
dc.subject | EXTRAHEPATIC BILE-DUCTS | - |
dc.subject | CARCINOID-TUMORS | - |
dc.subject | AMPULLA | - |
dc.subject | VATER | - |
dc.subject | EPIDEMIOLOGY | - |
dc.subject | FEATURES | - |
dc.subject | HETEROGENEITY | - |
dc.subject | GALLBLADDER | - |
dc.subject | SYSTEM | - |
dc.title | Clinicopathological characteristics of biliary neuroendocrine neoplasms: a multicenter study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000394602300012 | - |
dc.identifier.doi | 10.1080/00365521.2016.1261938 | - |
dc.identifier.bibliographicCitation | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, v.52, no.4, pp.437 - 441 | - |
dc.identifier.scopusid | 2-s2.0-85002125616 | - |
dc.citation.endPage | 441 | - |
dc.citation.startPage | 437 | - |
dc.citation.title | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | - |
dc.citation.volume | 52 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Cho, Jae Hee | - |
dc.contributor.affiliatedAuthor | Kim, Yeon Suk | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | World Health Organization classification | - |
dc.subject.keywordAuthor | biliary tract | - |
dc.subject.keywordAuthor | neuroendocrine neoplasm | - |
dc.subject.keywordAuthor | neuroendocrine carcinoma | - |
dc.subject.keywordAuthor | prognosis | - |
dc.subject.keywordPlus | EXTRAHEPATIC BILE-DUCTS | - |
dc.subject.keywordPlus | CARCINOID-TUMORS | - |
dc.subject.keywordPlus | AMPULLA | - |
dc.subject.keywordPlus | VATER | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | FEATURES | - |
dc.subject.keywordPlus | HETEROGENEITY | - |
dc.subject.keywordPlus | GALLBLADDER | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.