Chemoselective acylation of 2-amino-8-quinolinol in the generation of C2-amides or C8-esters
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Yongseok | - |
dc.contributor.author | Fei, Xiang | - |
dc.contributor.author | Yuan, Yue | - |
dc.contributor.author | Lee, Sanha | - |
dc.contributor.author | Hur, Joonseong | - |
dc.contributor.author | Park, Sung Jean | - |
dc.contributor.author | Jung, Jae-Kyung | - |
dc.contributor.author | Seo, Seung-Yong | - |
dc.date.available | 2020-02-27T23:42:13Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7518 | - |
dc.description.abstract | Two different ways to carry out the chemoselective acylation of 2-amino-8-quinolinol with unique features to generate C2-amides or C8-esters were developed. The coupling reaction with a variety of carboxylic acids using EDCI and DMAP provided C8-ester derivatives, whereas N-heteroaromatic acids were not introduced on the C8-hydroxy group, but rather on the C2-amino group under the same conditions. To obtain C2-amides selectively, the anionic nucleophile from 2-amino-8-quinolinol was treated with less reactive acyl imidazolides or esters. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.relation.isPartOf | RSC ADVANCES | - |
dc.subject | AMIDE BOND FORMATION | - |
dc.subject | 8-HYDROXYQUINOLINE DERIVATIVES | - |
dc.subject | COUPLING REAGENTS | - |
dc.subject | 2-AMINO-8-HYDROXYQUINOLINE | - |
dc.subject | PEPTIDE | - |
dc.subject | 2-AMINOQUINOLINES | - |
dc.subject | OPTIMIZATION | - |
dc.subject | INHIBITION | - |
dc.subject | AMIDATIONS | - |
dc.subject | FRAGMENT | - |
dc.title | Chemoselective acylation of 2-amino-8-quinolinol in the generation of C2-amides or C8-esters | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000409147500001 | - |
dc.identifier.doi | 10.1039/c7ra05287a | - |
dc.identifier.bibliographicCitation | RSC ADVANCES, v.7, no.67, pp.41955 - 41961 | - |
dc.identifier.scopusid | 2-s2.0-85028936094 | - |
dc.citation.endPage | 41961 | - |
dc.citation.startPage | 41955 | - |
dc.citation.title | RSC ADVANCES | - |
dc.citation.volume | 7 | - |
dc.citation.number | 67 | - |
dc.contributor.affiliatedAuthor | Park, Yongseok | - |
dc.contributor.affiliatedAuthor | Fei, Xiang | - |
dc.contributor.affiliatedAuthor | Yuan, Yue | - |
dc.contributor.affiliatedAuthor | Lee, Sanha | - |
dc.contributor.affiliatedAuthor | Park, Sung Jean | - |
dc.contributor.affiliatedAuthor | Seo, Seung-Yong | - |
dc.type.docType | Article | - |
dc.subject.keywordPlus | AMIDE BOND FORMATION | - |
dc.subject.keywordPlus | 8-HYDROXYQUINOLINE DERIVATIVES | - |
dc.subject.keywordPlus | COUPLING REAGENTS | - |
dc.subject.keywordPlus | 2-AMINO-8-HYDROXYQUINOLINE | - |
dc.subject.keywordPlus | PEPTIDE | - |
dc.subject.keywordPlus | 2-AMINOQUINOLINES | - |
dc.subject.keywordPlus | OPTIMIZATION | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | AMIDATIONS | - |
dc.subject.keywordPlus | FRAGMENT | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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