Miniaturized and Wireless Optical Neurotransmitter Sensor for Real-Time Monitoring of Dopamine in the Brain
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Min H. | - |
dc.contributor.author | Yoon, Hargsoon | - |
dc.contributor.author | Choi, Sang H. | - |
dc.contributor.author | Zhao, Fei | - |
dc.contributor.author | Kim, Jongsung | - |
dc.contributor.author | Song, Kyo D. | - |
dc.contributor.author | Lee, Uhn | - |
dc.date.available | 2020-02-28T00:41:39Z | - |
dc.date.created | 2020-02-07 | - |
dc.date.issued | 2016-11 | - |
dc.identifier.issn | 1424-8220 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/7754 | - |
dc.description.abstract | Real-time monitoring of extracellular neurotransmitter concentration offers great benefits for diagnosis and treatment of neurological disorders and diseases. This paper presents the study design and results of a miniaturized and wireless optical neurotransmitter sensor (MWONS) for real-time monitoring of brain dopamine concentration. MWONS is based on fluorescent sensing principles and comprises a microspectrometer unit, a microcontroller for data acquisition, and a Bluetooth wireless network for real-time monitoring. MWONS has a custom-designed application software that controls the operation parameters for excitation light sources, data acquisition, and signal processing. MWONS successfully demonstrated a measurement capability with a limit of detection down to a 100 nanomole dopamine concentration, and high selectivity to ascorbic acid (90:1) and uric acid (36:1). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | SENSORS | - |
dc.subject | SURFACE-ENHANCED RAMAN | - |
dc.subject | QUANTUM DOTS | - |
dc.subject | SELECTIVE DETECTION | - |
dc.subject | NEURONS | - |
dc.subject | MODULATION | - |
dc.subject | SCATTERING | - |
dc.subject | ASCORBATE | - |
dc.subject | NUCLEUS | - |
dc.title | Miniaturized and Wireless Optical Neurotransmitter Sensor for Real-Time Monitoring of Dopamine in the Brain | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000389641700127 | - |
dc.identifier.doi | 10.3390/s16111894 | - |
dc.identifier.bibliographicCitation | SENSORS, v.16, no.11 | - |
dc.identifier.scopusid | 2-s2.0-84995466580 | - |
dc.citation.title | SENSORS | - |
dc.citation.volume | 16 | - |
dc.citation.number | 11 | - |
dc.contributor.affiliatedAuthor | Zhao, Fei | - |
dc.contributor.affiliatedAuthor | Kim, Jongsung | - |
dc.contributor.affiliatedAuthor | Lee, Uhn | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | microspectrometer | - |
dc.subject.keywordAuthor | fluorescence | - |
dc.subject.keywordAuthor | dopamine | - |
dc.subject.keywordAuthor | optical sensing | - |
dc.subject.keywordAuthor | wireless | - |
dc.subject.keywordPlus | SURFACE-ENHANCED RAMAN | - |
dc.subject.keywordPlus | QUANTUM DOTS | - |
dc.subject.keywordPlus | SELECTIVE DETECTION | - |
dc.subject.keywordPlus | NEURONS | - |
dc.subject.keywordPlus | MODULATION | - |
dc.subject.keywordPlus | SCATTERING | - |
dc.subject.keywordPlus | ASCORBATE | - |
dc.subject.keywordPlus | NUCLEUS | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.