External Airborne-agent Exposure Increase Risk of Digestive Tract Cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee W. | - |
dc.contributor.author | Kim J. | - |
dc.contributor.author | Lim S.-S. | - |
dc.contributor.author | Kim Y. | - |
dc.contributor.author | Ahn Y.-S. | - |
dc.contributor.author | Yoon J.-H. | - |
dc.date.available | 2020-10-20T02:46:18Z | - |
dc.date.created | 2020-06-03 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/78449 | - |
dc.description.abstract | Previous studies have suggested that in addition to respiratory system cancers, exposure to external airborne agents (EAAs) may also affect the risk of digestive tract cancer. However, previous epidemiological studies have been limited. To clarify this relationship, we conducted a Workers’ Korea National Health Insurance Service cohort study. The EAA exposure group comprised participants who had ever visited a hospital as an inpatient for ‘lung diseases due to external agents’. The reference population comprised men from the general working population. The EAA exposure group and reference group included a total of 98,666 and 79,959,286 person-years, respectively. Age-adjusted standardized incident rates (SIRs) with 95% confidence intervals (95%CI) were calculated for each 5-year age stratum. The SIR (95% CI) of EAA exposure was 1.30 (1.19–1.38) for all digestive tract cancers. The highest risk associated with EAA exposure was observed for oral cancer, followed by esophageal and stomach cancers [SIRs (95%CI): 3.96 (3.02–4.78), 3.47(2.60–4.25), and 1.34(1.17–1.47), respectively.] These statistically significant associations did not be attenuated in a subgroup analysis using logistic regression adjusted for age, smoking and alcohol consumption. Our findings suggest that EAA exposure should address risk reduction of both digestive tract and respiratory system cancers. © 2020, The Author(s). | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Nature Research | - |
dc.relation.isPartOf | Scientific Reports | - |
dc.title | External Airborne-agent Exposure Increase Risk of Digestive Tract Cancer | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000560772000026 | - |
dc.identifier.doi | 10.1038/s41598-020-65312-6 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.10, no.1 | - |
dc.identifier.scopusid | 2-s2.0-85085326980 | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Lee W. | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.