Effect of Differential Thermal Drying Conditions on the Immunomodulatory Function of Ginger
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이지수 | - |
dc.contributor.author | 김보미 | - |
dc.contributor.author | 김재환 | - |
dc.contributor.author | 정민주 | - |
dc.contributor.author | 임석원 | - |
dc.contributor.author | 변상균 | - |
dc.date.available | 2020-10-20T06:44:00Z | - |
dc.date.created | 2020-06-10 | - |
dc.date.issued | 2019-07 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/78559 | - |
dc.description.abstract | Thermal drying is a common process used in the food industry for the modification of agricultural products. However, while various studies have investigated the alteration in physiochemical properties and chemical composition after drying, research focusing on the relationship between different dehydration conditions and bioactivity is scarce. In the current study, we prepared dried ginger under nine different conditions by varying the processing time and temperature and compared their immunomodulatory effects. Interestingly, depending on the drying condition, there were significant differences in the immunestimulating activity of the dried ginger samples. Gingers processed at 50oC 1h displayed the strongest activation of macrophages measured by TNF-α and IL-6 levels, whereas, freezedried or 70oC- and 90oC-dried ginger showed little effect. Similar results were recapitulated in primary bone marrow-derived macrophages, further confirming that different dehydration conditions can cause significant differences in the immune-stimulating activity of ginger. Induction of ERK, p38, and JNK signaling was found to be the major underlying molecular mechanism responsible for the immunomodulatory effect of ginger. These results highlight the potential to improve the bioactivity of functional foods by selectively controlling processing conditions | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 한국미생물·생명공학회 | - |
dc.relation.isPartOf | Journal of Microbiology and Biotechnology | - |
dc.title | Effect of Differential Thermal Drying Conditions on the Immunomodulatory Function of Ginger | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000477632900006 | - |
dc.identifier.doi | 10.4014/jmb.1905.05063 | - |
dc.identifier.bibliographicCitation | Journal of Microbiology and Biotechnology, v.29, no.7, pp.1053 - 1060 | - |
dc.identifier.kciid | ART002489013 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85070729412 | - |
dc.citation.endPage | 1060 | - |
dc.citation.startPage | 1053 | - |
dc.citation.title | Journal of Microbiology and Biotechnology | - |
dc.citation.volume | 29 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | 임석원 | - |
dc.subject.keywordAuthor | Thermal drying | - |
dc.subject.keywordAuthor | ginger | - |
dc.subject.keywordAuthor | immunomodulation | - |
dc.subject.keywordAuthor | MAPK pathway | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.