Polysaccharide-Rich Extract of Phragmites rhizome Attenuates Water Immersion Stress and Forced Swimming Fatigue in Rodent Animal Model
DC Field | Value | Language |
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dc.contributor.author | Chung, Yoon Hee | - |
dc.contributor.author | Park, Tae Kwang | - |
dc.contributor.author | Yim, Sung Hyuk | - |
dc.contributor.author | Lee, Jong Hyuk | - |
dc.contributor.author | Bang, Joon Seok | - |
dc.contributor.author | Shin, Yong Kyoo | - |
dc.contributor.author | Bae, Jinhyung | - |
dc.contributor.author | Sim, Sang Soo | - |
dc.contributor.author | Hwang, Kwang Woo | - |
dc.contributor.author | Shin, Chang Yell | - |
dc.contributor.author | Im, Wi Joon | - |
dc.contributor.author | Khin, Phyu Phyu | - |
dc.contributor.author | Lee, Jaehwi | - |
dc.contributor.author | Min, Young Sil | - |
dc.contributor.author | Jeong, Ji Hoon | - |
dc.contributor.author | Sohn, Uy Dong | - |
dc.date.available | 2020-10-20T06:44:24Z | - |
dc.date.created | 2020-08-31 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1096-620X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/78578 | - |
dc.description.abstract | Our study aimed to investigate the effects of the polysaccharide-rich extract of Phragmites rhizoma (PEP) against water immersion restraint (WIR) stress and forced swimming-induced fatigue. Exposure to WIR stress significantly increased the ulcer index, bleeding score, the weight of the adrenal gland, blood glucose concentrations, total cholesterol, cortisol, and creatine kinase (CK). The weight of the spleen decreased significantly. In addition, myeloperoxidase (MPO) and thiobarbituric acid-reactive substance (TBARS) were significantly upregulated by WIR stress. The antioxidative factors such as glutathione (GSH) and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in the stomach were decreased by WIR stress. Alterations induced by WIR stress were effectively reversed by pretreatment with PEP. The swimming endurance capacity of mice was significantly prolonged by the oral administration of PEP. Swimming-induced fatigue significantly reduced the body weight; however, the injection of PEP inhibited the decrease of body weight. The PEP-treated group had significantly lower CK levels in plasma, an indicator of muscle damage. These results indicated that PEP has anti-stress and anti-fatigue effects, which are mediated by suppressing the hyperactivation of the hypothalamus-pituitary-adrenal axis, and antagonism of the oxidative damages induced by WIR stress and prolonged swimming times. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MARY ANN LIEBERT, INC | - |
dc.relation.isPartOf | JOURNAL OF MEDICINAL FOOD | - |
dc.title | Polysaccharide-Rich Extract of Phragmites rhizome Attenuates Water Immersion Stress and Forced Swimming Fatigue in Rodent Animal Model | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000465046500004 | - |
dc.identifier.doi | 10.1089/jmf.2018.4218 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MEDICINAL FOOD, v.22, no.4, pp.355 - 364 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 364 | - |
dc.citation.startPage | 355 | - |
dc.citation.title | JOURNAL OF MEDICINAL FOOD | - |
dc.citation.volume | 22 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Khin, Phyu Phyu | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | anti-fatigue | - |
dc.subject.keywordAuthor | anti-stress | - |
dc.subject.keywordAuthor | oxidative damage | - |
dc.subject.keywordAuthor | polysaccharide-rich extract of Phragmites rhizoma (PEP) | - |
dc.subject.keywordAuthor | water immersion restraint (WIR)-induced stress | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | LIPID-PEROXIDATION | - |
dc.subject.keywordPlus | ENZYME-ACTIVITIES | - |
dc.subject.keywordPlus | EXERCISE | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | DEPRESSION | - |
dc.subject.keywordPlus | GLUCOCORTICOIDS | - |
dc.subject.keywordPlus | MELANOGENESIS | - |
dc.subject.keywordPlus | GLUTATHIONE | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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