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Three new oleanane-type triterpenoidal glycosides from impatiens balsamina and their biological activity

Authors
Lee, T.H.Suh, W.S.Subedi, L.Kim, S.Y.Choi, S.U.Lee, K.R.Kim, C.S.
Issue Date
Sep-2020
Publisher
MDPI AG
Keywords
Anti-neuroinflammation; Balsaminaceae; Cytotoxicity; Impatiens balsamina; Triterpenoidal glycosides
Citation
Plants, v.9, no.9, pp.1 - 9
Journal Title
Plants
Volume
9
Number
9
Start Page
1
End Page
9
URI
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/78853
DOI
10.3390/plants9091083
ISSN
2223-7747
Abstract
Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (1–3), were isolated from the white flowers of Impatiens balsamina. The structures of these phytochemical constituents (1–3) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses followed by chemical methods. All the characterized compounds (1–3) were evaluated for their antiproliferative activity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and BT549) and their anti-neuroinflammatory activity on the basis of inhibition levels of nitric oxide (NO) in the lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cell lines. © 2020 by the authors. Licensee MDPI, Basel, Switzerland.
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