The role of allergen-specific IgE in predicting allergic symptoms on dog and cat exposure among Korean pet exhibition participants
DC Field | Value | Language |
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dc.contributor.author | Kang, S.-Y. | - |
dc.contributor.author | Yang, M.-S. | - |
dc.contributor.author | Park, S.-Y. | - |
dc.contributor.author | Kim, J.-H. | - |
dc.contributor.author | Won, H.-K. | - |
dc.contributor.author | Kwon, O.Y. | - |
dc.contributor.author | Lee, J.-H. | - |
dc.contributor.author | Kang, Y.-W. | - |
dc.contributor.author | Jung, J.-W. | - |
dc.contributor.author | Song, W.-J. | - |
dc.contributor.author | Kim, S.-H. | - |
dc.contributor.author | Lee, S.M. | - |
dc.contributor.author | Lee, S.P. | - |
dc.date.available | 2021-01-20T00:40:22Z | - |
dc.date.created | 2020-12-07 | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 1939-4551 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/79784 | - |
dc.description.abstract | Background: The values of the skin prick test (SPT) and allergen-specific IgE (sIgE) measurement in predicting dog and cat allergies remain unclear. We aimed to evaluate the usefulness of SPT and sIgE measurement in predicting self-reported allergic symptoms during exposure to dogs and cats in Korean adults. Methods: A total of 552 participants in a pet exhibition in Korea completed questionnaires regarding exposure to dog or cat and the development of allergic symptoms during exposure. Study participants also underwent SPT using 3 different commercially available reagents, and had their blood drawn for measurement of serum total IgE and dog/cat-dander-IgE using ImmunoCAP®. Results: Measurement of sIgE for dog and cat dander allergens provided the highest positive and negative predictive values and sensitivity, but not specificity (58%, 87.2%, 67.9%, and 93.1% for allergic symptoms on dog exposure; 64.7%, 83.2%, 74.8%, and 88.9% for those on cat exposure, respectively), in predicting self-reported allergic symptoms on dog and cat exposure. The sIgE level consistently exhibited the highest area under the receiver operating characteristic curve (0.749 and 0.719 for allergic symptoms on dog and cat exposure, respectively). Careful interpretation of SPT and sIgE measurements maximized the positive and negative predictive values, sensitivity, and specificity for predicting allergic symptoms on dog exposure (71.4%, 87.3%, 75.3%, and 99.3%) and those on cat exposure (71.4%, 85.3%, 79.3%, and 98.9%). Conclusions: The measurement of dog and cat dander sIgE levels may be useful for the exclusion of allergic symptoms related to pet exposure. Collective interpretation of SPT and sIgE tests facilitates identification of allergic symptoms on dog or cat exposure, giving a better rule-in test result. © 2020 The Authors | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.relation.isPartOf | World Allergy Organization Journal | - |
dc.title | The role of allergen-specific IgE in predicting allergic symptoms on dog and cat exposure among Korean pet exhibition participants | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000604190600009 | - |
dc.identifier.doi | 10.1016/j.waojou.2020.100488 | - |
dc.identifier.bibliographicCitation | World Allergy Organization Journal, v.13, no.12 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85096855282 | - |
dc.citation.title | World Allergy Organization Journal | - |
dc.citation.volume | 13 | - |
dc.citation.number | 12 | - |
dc.contributor.affiliatedAuthor | Kang, S.-Y. | - |
dc.contributor.affiliatedAuthor | Lee, S.M. | - |
dc.contributor.affiliatedAuthor | Lee, S.P. | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Allergy | - |
dc.subject.keywordAuthor | Cats | - |
dc.subject.keywordAuthor | Dogs | - |
dc.subject.keywordAuthor | Skin prick test | - |
dc.subject.keywordAuthor | Specific IgE | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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