Cough persistence in adults with chronic cough: A 4-year retrospective cohort study
DC Field | Value | Language |
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dc.contributor.author | Kang, Sung-Yoon | - |
dc.contributor.author | Song, Woo-Jung | - |
dc.contributor.author | Won, Ha-Kyeong | - |
dc.contributor.author | Chung, Soo Jie | - |
dc.contributor.author | Kim, Ju-Young | - |
dc.contributor.author | Park, Heung-Woo | - |
dc.contributor.author | Morice, Alyn H. | - |
dc.contributor.author | Cho, Sang-Heon | - |
dc.date.available | 2021-02-03T00:40:22Z | - |
dc.date.created | 2020-04-28 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 1323-8930 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/79882 | - |
dc.description.abstract | Background: There is very limited evidence regarding long-term prognosis of chronic cough. We examined longitudinal outcomes among patients with chronic cough, and explored predictors of cough persistence. Methods: A retrospective cohort was constructed of adults who had newly visited a specialist cough clinic in 2012–2013. All had undergone systematic investigation for chronic cough. The Hull Airway Reflux Questionnaire (HARQ) was administered to assess reflux cough symptoms. A follow-up survey was conducted in 2016–2017 to assess cough persistence. Results: From 418 candidates, 323 participated in the follow-up study; main analyses focused on patients with chronic persistent cough (n = 64; 19.8%) and remitted cough (n = 193; 59.8%). Compared with remitted cough group, chronic persistent cough group had more family history of chronic cough (17.2% vs. 4.7%, p = 0.001) and cold air-sensitive cough (62.5% vs. 44.6%, p = 0.013). The total HARQ score did not differ; however, two items (cough with eating and cough with certain foods) scored significantly higher in chronic persistent cough. In multivariate analyses, a family history of chronic cough (adjusted odds ratio 4.27 [95% confidence interval 1.35–9.89]), cold air-sensitive cough (2.01 [1.09–3.73]), and cough with eating (1.22 [1.02–1.45]) were associated with chronic persistent cough at 4 years. Conclusions: Cough persists in about 20% of patients after 4 years following systematic assessment and treatments. Several cough characteristics, such as family history, cold air-sensitivity, or reflux cough, may be associated with cough persistence. Larger cohort studies are warranted to further understand long-term prognosis and confirm predictors of persistence in patients with chronic cough. © 2020 Japanese Society of Allergology | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Japanese Society of Allergology | - |
dc.relation.isPartOf | Allergology International | - |
dc.title | Cough persistence in adults with chronic cough: A 4-year retrospective cohort study | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000607906900011 | - |
dc.identifier.doi | 10.1016/j.alit.2020.03.012 | - |
dc.identifier.bibliographicCitation | Allergology International, v.69, no.4, pp.588 - 593 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85083291036 | - |
dc.citation.endPage | 593 | - |
dc.citation.startPage | 588 | - |
dc.citation.title | Allergology International | - |
dc.citation.volume | 69 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Kang, Sung-Yoon | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Chronic cough | - |
dc.subject.keywordAuthor | Epidemiology | - |
dc.subject.keywordAuthor | Longitudinal outcome | - |
dc.subject.keywordAuthor | Predictor | - |
dc.subject.keywordAuthor | Retrospective cohort study | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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