Dosimetric Impact of Respiratory Motion During Breast Intensity-modulated Radiation Therapy Using Four-dimensional Dose Calculations
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Young Eun | - |
dc.contributor.author | Sung, Kihoon | - |
dc.contributor.author | Dong, Kap Sang | - |
dc.contributor.author | Kim, Hyun Ju | - |
dc.contributor.author | Lim, Young-khi | - |
dc.date.available | 2021-02-16T01:40:53Z | - |
dc.date.created | 2021-02-01 | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 0250-7005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/79951 | - |
dc.description.abstract | Background/Aim: The use of intensity-modulated radiation therapy (IMRT) in the treatment of breast cancer is increasing worldwide. Despite clear benefits concerning normal tissue sparing and dose homogeneity, the effects of breathing motion and setup error during breast IMRT should be considered. This study aimed to assess the dosimetric impact of respiratory motion on breast IMRT using fourdimensional (4D) dose calculations. Patients and Methods: Multiple computed tomography datasets acquired in three representative respiratory amplitudes, were retrospectively replanned. Based on the reference dose distribution (RDD), motion-adjusted dose distributions (MDD) were recalculated. All 4D dose distributions were calculated by the voxel-based accumulation of RDD and MDD using five temporal probabilities. The dosimetric parameters of the 4D plans were compared to those of RDD. Results: The dosimetric parameters of the planning target volume (PTV) were not significantly different between the RDD and 4D plans. Of the parameters of tumor bed (TB) simultaneous-integrated boost (SIB), the mean dose and V95% for the 4D plans were significantly reduced compared to those of RDD, and the percentage difference in the TB V95% ranged from -1.1% to -5.7% (p<0.05). Conclusion: The breast IMRT plan was robust against respiratory motion during tidal breathing. However, special considerations should be made when designing the TB SIB. © 2021 International Institute of Anticancer Research. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | INT INST ANTICANCER RESEARCH | - |
dc.relation.isPartOf | Anticancer Research | - |
dc.title | Dosimetric Impact of Respiratory Motion During Breast Intensity-modulated Radiation Therapy Using Four-dimensional Dose Calculations | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000608664500021 | - |
dc.identifier.doi | 10.21873/anticanres.14791 | - |
dc.identifier.bibliographicCitation | Anticancer Research, v.41, no.1, pp.417 - 427 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85099715405 | - |
dc.citation.endPage | 427 | - |
dc.citation.startPage | 417 | - |
dc.citation.title | Anticancer Research | - |
dc.citation.volume | 41 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Choi, Young Eun | - |
dc.contributor.affiliatedAuthor | Sung, Kihoon | - |
dc.contributor.affiliatedAuthor | Dong, Kap Sang | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Ju | - |
dc.contributor.affiliatedAuthor | Lim, Young-khi | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | 4D dose calculation | - |
dc.subject.keywordAuthor | Breast cancer | - |
dc.subject.keywordAuthor | Deformable image registration | - |
dc.subject.keywordAuthor | IMRT | - |
dc.subject.keywordAuthor | Respiratory motion | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.