Association between continuous deep sedation and survival time in terminally ill cancer patients
DC Field | Value | Language |
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dc.contributor.author | Park, So-Jung | - |
dc.contributor.author | Ahn, Hee Kyung | - |
dc.contributor.author | Ahn, Hong Yup | - |
dc.contributor.author | Han, Kyu-Tae | - |
dc.contributor.author | Hwang, In Cheol | - |
dc.date.available | 2021-02-22T01:40:05Z | - |
dc.date.created | 2020-05-28 | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 0941-4355 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80004 | - |
dc.description.abstract | Purpose Our study aimed to evaluate the association between CDS and survival time using the likelihood of receiving CDS to select a matched non-CDS group through an accurate measurement of survival time based on initiation of CDS. Methods A retrospective cohort study was performed using an electronic database to collect data regarding terminally ill cancer patients admitted to a specialized palliative care unit from January 2012 to December 2016. We first used a Cox proportional hazard model with receiving CDS as the outcome to identify individuals with the highest plausibility of receiving CDS among the non-CDS group (n = 663). We then performed a multiple regression analysis comparing the CDS group (n = 311) and weighted non-CDS group (n = 311), using initiation of CDS (actual for the CDS group; estimated for the non-CDS group) as the starting time-point for measuring survival time. Results Approximately 32% of participants received CDS. The most common indications were delirium or agitation (58.2%), intractable pain (28.9%), and dyspnea (10.6%). Final multiple regression analysis revealed that survival time was longer in the CDS group than in the non-CDS group (Exp(beta), 1.41; P < 0.001). Longer survival with CDS was more prominent in females, patients with renal dysfunction, and individuals with low C-reactive protein (CRP) or ferritin, compared with their counterpart subgroup. Conclusions CDS was not associated with shortened survival; instead, it was associated with longer survival in our terminally ill cancer patients. Further studies in other populations are required to confirm or refute these findings. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | SPRINGER | - |
dc.relation.isPartOf | SUPPORTIVE CARE IN CANCER | - |
dc.title | Association between continuous deep sedation and survival time in terminally ill cancer patients | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000533038800001 | - |
dc.identifier.doi | 10.1007/s00520-020-05516-8 | - |
dc.identifier.bibliographicCitation | SUPPORTIVE CARE IN CANCER, v.29, no.1, pp.525 - 531 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85084810143 | - |
dc.citation.endPage | 531 | - |
dc.citation.startPage | 525 | - |
dc.citation.title | SUPPORTIVE CARE IN CANCER | - |
dc.citation.volume | 29 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Ahn, Hee Kyung | - |
dc.contributor.affiliatedAuthor | Hwang, In Cheol | - |
dc.type.docType | Article; Early Access | - |
dc.subject.keywordAuthor | Continuous deep sedation | - |
dc.subject.keywordAuthor | Palliative sedation | - |
dc.subject.keywordAuthor | Survival | - |
dc.subject.keywordAuthor | Sedative | - |
dc.subject.keywordAuthor | Palliative care | - |
dc.subject.keywordAuthor | Hospice | - |
dc.subject.keywordPlus | PALLIATIVE SEDATION | - |
dc.subject.keywordPlus | REFRACTORY SYMPTOMS | - |
dc.subject.keywordPlus | CARE | - |
dc.subject.keywordPlus | END | - |
dc.subject.keywordPlus | LIFE | - |
dc.subject.keywordPlus | NETHERLANDS | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordPlus | PAIN | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Health Care Sciences & Services | - |
dc.relation.journalResearchArea | Rehabilitation | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Health Care Sciences & Services | - |
dc.relation.journalWebOfScienceCategory | Rehabilitation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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