Chiral Derivatization of Hydroxycarboxylic Acids Using 2,4,6-Trichlorobenzoyl Chloride as a Highly Efficient Regioselective Esterification Reagent for Gas Chromatography-Mass Spectrometry
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jeong Hyeok | - |
dc.contributor.author | Han, Sang Yun | - |
dc.date.available | 2021-03-09T02:40:06Z | - |
dc.date.created | 2021-01-08 | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 2233-4203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80336 | - |
dc.description.abstract | We report the application of 2,4,6-trichlorobenzoyl chloride (often referred to as Yamaguchi esterification reagent) for the selective derivatization of the carboxylic group for GC-MS with the sample preparation method optimized for GC-MS analysis. The reagent was shown to be capable of selectively turning the carboxylic group into a reaction center, i.e., anhydride, of which the further reaction was directed to a near complete formation of required esters by unique steric and electronic effects of the reagent. Using the developed method, the chiral separation of hydroxycarboxylic acids by GC-MS using non-chiral col- umns was successfully demonstrated. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | 사단법인 한국질량분석학회 | - |
dc.relation.isPartOf | Mass Spectrometry Letters | - |
dc.title | Chiral Derivatization of Hydroxycarboxylic Acids Using 2,4,6-Trichlorobenzoyl Chloride as a Highly Efficient Regioselective Esterification Reagent for Gas Chromatography-Mass Spectrometry | - |
dc.title.alternative | Chiral Derivatization of Hydroxycarboxylic Acids Using 2,4,6-Trichlorobenzoyl Chloride as a Highly Efficient Regioselective Esterification Reagent for Gas Chromatography-Mass Spectrometry | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000627793700007 | - |
dc.identifier.doi | 10.5478/MSL.2020.11.4.103 | - |
dc.identifier.bibliographicCitation | Mass Spectrometry Letters, v.11, no.4, pp.103 - 107 | - |
dc.identifier.kciid | ART002674417 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85101534884 | - |
dc.citation.endPage | 107 | - |
dc.citation.startPage | 103 | - |
dc.citation.title | Mass Spectrometry Letters | - |
dc.citation.volume | 11 | - |
dc.citation.number | 4 | - |
dc.contributor.affiliatedAuthor | Park, Jeong Hyeok | - |
dc.contributor.affiliatedAuthor | Han, Sang Yun | - |
dc.subject.keywordAuthor | 2 | - |
dc.subject.keywordAuthor | 4 | - |
dc.subject.keywordAuthor | 6-trichlorobenzoyl chloride | - |
dc.subject.keywordAuthor | chiral separation | - |
dc.subject.keywordAuthor | GC-MS | - |
dc.subject.keywordAuthor | hydroxycarboxylic acids | - |
dc.subject.keywordAuthor | O-acetylated L-menthyl esters | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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