CONSORT the effect of a bolus dose of dexmedetomidine on postoperative pain, agitation, and quality of recovery after laparoscopic cholecystectomy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Jung Ju | - |
dc.contributor.author | Kim, Kyungmi | - |
dc.contributor.author | Park, Hee Yeon | - |
dc.contributor.author | Chang, Young Jin | - |
dc.contributor.author | Lee, Kyung Cheon | - |
dc.contributor.author | Kim, Kwan Yeong | - |
dc.contributor.author | Kwak, Hyun Jeong | - |
dc.date.available | 2021-03-11T00:40:18Z | - |
dc.date.created | 2021-03-11 | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80368 | - |
dc.description.abstract | Background: The perioperative administration of dexmedetomidine may improve the quality of recovery (QoR) after major abdominal and spinal surgeries. We evaluated the effect of an intraoperative bolus of dexmedetomidine on postoperative pain, emergence agitation, and the QoR after laparoscopic cholecystectomy. Methods: Patients undergoing elective laparoscopic cholecystectomy were randomized to receive dexmedetomidine 0.5 mu g/kg 5 minutes after anesthesia induction (dexmedetomidine group, n = 45) or normal saline (control group, n = 45). The primary outcome was the QoR at the first postoperative day using a 40-item scoring system (QoR-40). Secondary outcomes included intraoperative hemodynamic parameters, postoperative agitation, pain, and nausea and vomiting. Results: The heart rate and the mean blood pressure were significantly lower in the dexmedetomidine group than in the control group (P < .001 and .007, respectively). During extubation, emergence agitation was significantly lower in the dexmedetomidine group than in the control group (23% vs 64%, P < .001). The median pain scores in the post-anesthetic care unit were significantly lower in the dexmedetomidine group than in the control group (4 [2-7] vs 5 [4-7], P = .034). The incidence of postoperative agitation, pain, and nausea and vomiting was not different between the groups. On the first postoperative day, recovery profile was similar between the groups. However, the scores on the emotional state and physical comfort dimensions were significantly higher in the dexmedetomidine group than in the control group (P = .038 and .040, respectively). Conclusions: A bolus dose of dexmedetomidine after anesthesia induction may improve intraoperative hemodynamics, emergence agitation, and immediate postoperative analgesia. However, it does not affect overall QoR-40 score after laparoscopic cholecystectomy. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | MEDICINE | - |
dc.title | CONSORT the effect of a bolus dose of dexmedetomidine on postoperative pain, agitation, and quality of recovery after laparoscopic cholecystectomy | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000612835100149 | - |
dc.identifier.doi | 10.1097/MD.0000000000024353 | - |
dc.identifier.bibliographicCitation | MEDICINE, v.100, no.3 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85102089311 | - |
dc.citation.title | MEDICINE | - |
dc.citation.volume | 100 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Choi, Jung Ju | - |
dc.contributor.affiliatedAuthor | Park, Hee Yeon | - |
dc.contributor.affiliatedAuthor | Chang, Young Jin | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Cheon | - |
dc.contributor.affiliatedAuthor | Kim, Kwan Yeong | - |
dc.contributor.affiliatedAuthor | Kwak, Hyun Jeong | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | dexmedetomidine | - |
dc.subject.keywordAuthor | emergence agitation | - |
dc.subject.keywordAuthor | laparoscopic cholecystectomy | - |
dc.subject.keywordAuthor | quality of recovery | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
1342, Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do, Republic of Korea(13120)031-750-5114
COPYRIGHT 2020 Gachon University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.