Relationship of Bone Mineral Density and Knee Osteoarthritis (Kellgren-Lawrence Grade): Fifth Korea National Health and Nutrition Examination Survey
DC Field | Value | Language |
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dc.contributor.author | Choi, Eun-Seok | - |
dc.contributor.author | Shin, Hyun Dae | - |
dc.contributor.author | Sim, Jae Ang | - |
dc.contributor.author | Na, Young Gon | - |
dc.contributor.author | Choi, Won-Jun | - |
dc.contributor.author | Shin, Dae-Do | - |
dc.contributor.author | Baik, Jong-Min | - |
dc.date.available | 2021-03-25T00:40:17Z | - |
dc.date.created | 2021-03-25 | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 2005-291X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80539 | - |
dc.description.abstract | Background: Osteoarthritis (OA) and osteoporosis (OP) are the 2 most common bone disorders associated with aging. We can simply assume that older patients have a higher incidence of OA and OP with more severity. Although several papers have conducted studies on the relationship between OA and OP, none of them has demonstrated a conclusive link. In this study, we used radiological knee OA and bone mineral density (BMD; T-score of the total hip and lumbar spine) to analyze the incidence of OA and OP in a large population. We aimed to determine the relationship between OA and OP and investigate the associated risk factors. Methods: This cross-sectional study used data extracted from the 2010–2012 Korea National Health and Nutrition Examination Survey. We evaluated a total of 4,250 participants aged ≥ 50 years who underwent knee radiography and dual-energy X-ray absorptiometry and their laboratory results. The relationship between radiological knee OA and BMD was assessed. The generalized linear model was used to evaluate the relationship between BMD and Kellgren-Lawrence (KL) grade. Results: The higher KL grade was associated with older age, higher body mass index (BMI), female sex, and lower hemoglobin level (p < 0.001). No significant association was found between OA and the following variables: white blood cell, platelet, total cholesterol, vitamin D, alkaline phosphatase, parathyroid hormone, hypertension, diabetes, asthma, dyslipidemia, smoking status, alcohol consumption, and regular exercise (p > 0.05). After adjusting for confounding factors (age, BMI, diabetes, hypertension, smoking, and alcohol consumption), the average T-scores of total hip and lumbar spine were the highest in the mild OA group with KL grade 2 (–0.22 ± 1.08 and –0.89 ± 1.46, respectively, p < 0.001). The average T-scores of the total hip and lumbar spine significantly decreased as OA progressed from moderate (KL grade 3; –0.49 ± 1.05 and –1.33 ± 1.38, respectively, p < 0.001) to severe (KL grade 4; –0.73 ± 1.13 and –1.74 ± 1.75, respectively, p < 0.001). T-scores of the moderate-to-severe OA group were significantly lower than those of the non-OA group (KL grades 0 and 1, p < 0.001). Conclusions: Compared with the non-OA group, BMD (T-scores of the total hip and lumbar spine) was higher in the mild OA group and lower in the moderate-to-severe OA group. © 2021 by The Korean Orthopaedic Association. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Orthopaedic Association | - |
dc.relation.isPartOf | Clinics in Orthopedic Surgery | - |
dc.title | Relationship of Bone Mineral Density and Knee Osteoarthritis (Kellgren-Lawrence Grade): Fifth Korea National Health and Nutrition Examination Survey | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000626257400009 | - |
dc.identifier.doi | 10.4055/cios20111 | - |
dc.identifier.bibliographicCitation | Clinics in Orthopedic Surgery, v.13, no.1, pp.60 - 66 | - |
dc.identifier.kciid | ART002788276 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85102676884 | - |
dc.citation.endPage | 66 | - |
dc.citation.startPage | 60 | - |
dc.citation.title | Clinics in Orthopedic Surgery | - |
dc.citation.volume | 13 | - |
dc.citation.number | 1 | - |
dc.contributor.affiliatedAuthor | Sim, Jae Ang | - |
dc.contributor.affiliatedAuthor | Choi, Won-Jun | - |
dc.contributor.affiliatedAuthor | Shin, Dae-Do | - |
dc.contributor.affiliatedAuthor | Baik, Jong-Min | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | Kellgren-Lawrence grade | - |
dc.subject.keywordAuthor | Korea National Health and Nutrition Examination Survey | - |
dc.subject.keywordAuthor | Osteoarthritis | - |
dc.subject.keywordAuthor | Osteoporosis | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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