Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors A Retrospective Nationwide Multicenter Study in South Korea
DC Field | Value | Language |
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dc.contributor.author | Cho, Jae Hee | - |
dc.contributor.author | Ryu, Ji Kon | - |
dc.contributor.author | Song, Si Young | - |
dc.contributor.author | Hwang, Jin-Hyeok | - |
dc.contributor.author | Lee, Dong Ki | - |
dc.contributor.author | Woo, Sang Myung | - |
dc.contributor.author | Joo, Young-Eun | - |
dc.contributor.author | Jeong, Seok | - |
dc.contributor.author | Lee, Seung-Ok | - |
dc.contributor.author | Park, Byung Kyu | - |
dc.contributor.author | Cheon, Young Koog | - |
dc.contributor.author | Han, Jimin | - |
dc.contributor.author | Kim, Tae Nyeun | - |
dc.contributor.author | Lee, Jun Kyu | - |
dc.contributor.author | Moon, Sung-Hoon | - |
dc.contributor.author | Kim, Hyunjin | - |
dc.contributor.author | Park, Eun Taek | - |
dc.contributor.author | Hwang, Jae Chul | - |
dc.contributor.author | Kim, Tae Hyeon | - |
dc.contributor.author | Jeon, Tae Joo | - |
dc.contributor.author | Cho, Chang-Min | - |
dc.contributor.author | Choi, Ho Soon | - |
dc.contributor.author | Lee, Woo Jin | - |
dc.date.available | 2020-02-28T01:42:12Z | - |
dc.date.created | 2020-02-06 | - |
dc.date.issued | 2016-08 | - |
dc.identifier.issn | 0885-3177 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/8069 | - |
dc.description.abstract | Objectives: Pancreatic neuroendocrine tumors (pNETs) are diverse diseases with different prognosis. The American Joint Committee on Cancer (AJCC) and the European Neuroendocrine Tumor Society (ENETS) introduced 2 different tumor node metastasis (TNM) stages, and the World Health Organization (WHO) proposed WHO 2010 grading system for pNETs. Therefore, we aimed to validate the prognostic relevance of these 3 systems for pNETs in South Korea. Methods: The Korean Society of Gastrointestinal Cancer created a retrospective registry of pNETs in 153 patients from 15 hospitals between 2002 and 2012. Results: On the basis of the WHO 2010 grade, 2-year progression-free-survival (PFS) rates for G1, G2, and G3 were 92%, 62%, and 25% (P < 0.01). According to ENETS and AJCC staging, 2-year PFS rates for stages I through IV were 94%, 87%, 49%, 20%, and 92%, 61%, 60%, 20%, respectively (P < 0.01). A Cox multivariate regression analysis revealed that the only statistically significant prognostic factor was the TNM classification of either the AJCC or the ENETS stage (P < 0.01). In addition, the. value between the AJCC and the ENETS stages was 0.46 indicating a "moderate" agreement (P < 0.01). Conclusions: The AJCC and ENETS TNM classifications for pNETs are prognostic for PFS and can be adopted in clinical practice in South Korea. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.relation.isPartOf | PANCREAS | - |
dc.subject | GEP-NETS | - |
dc.subject | SURVIVAL | - |
dc.subject | EPIDEMIOLOGY | - |
dc.subject | GUIDELINES | - |
dc.subject | EXPERIENCE | - |
dc.subject | NEOPLASMS | - |
dc.subject | DIAGNOSIS | - |
dc.subject | PATTERNS | - |
dc.subject | TRENDS | - |
dc.title | Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors A Retrospective Nationwide Multicenter Study in South Korea | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000380225900009 | - |
dc.identifier.doi | 10.1097/MPA.0000000000000586 | - |
dc.identifier.bibliographicCitation | PANCREAS, v.45, no.7, pp.941 - 946 | - |
dc.identifier.scopusid | 2-s2.0-84979513587 | - |
dc.citation.endPage | 946 | - |
dc.citation.startPage | 941 | - |
dc.citation.title | PANCREAS | - |
dc.citation.volume | 45 | - |
dc.citation.number | 7 | - |
dc.contributor.affiliatedAuthor | Cho, Jae Hee | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | pancreatic neuroendocrine tumors | - |
dc.subject.keywordAuthor | prognosis | - |
dc.subject.keywordAuthor | grading | - |
dc.subject.keywordAuthor | staging | - |
dc.subject.keywordPlus | GEP-NETS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | EXPERIENCE | - |
dc.subject.keywordPlus | NEOPLASMS | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordPlus | TRENDS | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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