A Cationic Surfactant-Decorated Liquid Crystal-Based Aptasensor for Label-Free Detection of Malathion Pesticides in Environmental Samples
DC Field | Value | Language |
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dc.contributor.author | Nguyen, Duy Khiem | - |
dc.contributor.author | Jang, Chang-Hyun | - |
dc.date.available | 2021-04-14T00:40:16Z | - |
dc.date.created | 2021-04-14 | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 2079-6374 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/80724 | - |
dc.description.abstract | We report a liquid crystal (LC)-based aptasensor for the detection of malathion using a cationic surfactant-decorated LC interface. In this method, LCs displayed dark optical images when in contact with aqueous cetyltrimethylammonium bromide (CTAB) solution due to the formation of a self-assembled CTAB monolayer at the aqueous/LC interface, which induced the homeotropic orientation of LCs. With the addition of malathion aptamer, the homeotropic orientation of LCs changed to a planar one due to the interactions between CTAB and the aptamer, resulting in a bright optical image. In the presence of malathion, the formation of aptamer-malathion complexes caused a conformational change of the aptamers, thereby weakening the interactions between CTAB and the aptamers. Therefore, CTAB is free to induce a homeotropic ordering of the LCs, which corresponds to a dark optical image. The developed sensor exhibited high specificity for malathion determination and a low detection limit of 0.465 nM was achieved. Moreover, the proposed biosensor was successfully applied to detect malathion in tap water, river water, and apple samples. The proposed LC-based aptasensor is a simple, rapid, and convenient platform for label-free monitoring of malathion in environmental samples. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | BIOSENSORS-BASEL | - |
dc.title | A Cationic Surfactant-Decorated Liquid Crystal-Based Aptasensor for Label-Free Detection of Malathion Pesticides in Environmental Samples | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.identifier.wosid | 000633397000001 | - |
dc.identifier.doi | 10.3390/bios11030092 | - |
dc.identifier.bibliographicCitation | BIOSENSORS-BASEL, v.11, no.3 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85103862672 | - |
dc.citation.title | BIOSENSORS-BASEL | - |
dc.citation.volume | 11 | - |
dc.citation.number | 3 | - |
dc.contributor.affiliatedAuthor | Nguyen, Duy Khiem | - |
dc.contributor.affiliatedAuthor | Jang, Chang-Hyun | - |
dc.type.docType | Article | - |
dc.subject.keywordAuthor | malathion | - |
dc.subject.keywordAuthor | liquid crystals | - |
dc.subject.keywordAuthor | liquid crystal biosensor | - |
dc.subject.keywordAuthor | pesticides | - |
dc.subject.keywordAuthor | DNA aptamer | - |
dc.subject.keywordAuthor | polarized light microscopy | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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